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Snakehead Consumption Enhances Wound Healing? From Tradition to Modern Clinical Practice: A Prospective Randomized Controlled Trial
المؤلفون المشاركون
Hayati, Firdaus
Zakaria, Andee Dzulkarnaen
Sahid, Nik Amin
Rao, Challa Venkata
Ramely, Rosnelifaizur
Sani, Ikhwan
Zakaria, Zaidi
Hassan, Syed
Zahari, Arman
Ali, Aishath Azna
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-14
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Snakehead fish (Channa striatus) is a fresh water fish indigenous to many Asia countries and believed to have medical value.
Studies showed that it contains all the essential amino acids and fatty acids able to accelerate wound healing and it has antinociceptive effect.
However, little human study has been done to assess the effectiveness of Channa striatus in wound healing.
A prospective RCT has been conducted on the effect of Channa striatus spray versus placebo on clean wound to assess its pain control effect and cosmetic outcome.
Methodology.
One hundred and two patients (102) underwent clean elective surgery; postoperatively they were randomized into two group.
One group received Channa striatus extract spray (n=51) another group received placebo (n=51) on daily basis for 2 weeks.
They were followed up on 2nd, 4th, and 6th weeks.
Pain control effect was assessed based on Visual Analog Pain Score (VAPS) and cosmetic outcome based on Visual Analog Cosmetic Scale (VACS), Wound Evaluation Scale (WES), and Vancouver Scar Scale (VSS).
Result.
The patient treated with Channa striatus spray displayed a better outcome in terms of pain control compared to placebo.
During analysis using repeated measure ANOVA, there was significant difference of patient’s pain score based on VAPS between Channa striatus spray and placebo (F-stat (df) = 4.80 (2), p-value = 0.010).
For cosmetic outcome it showed a better result in Channa striatus spray group for all the 3-scoring system, VACS, (F-stat (df) = 2.68 (2) , p-value <0.001), WES (F-stat (df) = 3.09 (2), p-value = 0.048), and VSS (F-stat (df) = 1.72 (2) , p-value = 0.011).
Conclusion.
Our study suggest that application of Channa striatus extract spray on clean wound has shown a significant better pain score result and cosmetic outcome on week 2, week 4, and week 6 comparatively with placebo.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sahid, Nik Amin& Hayati, Firdaus& Rao, Challa Venkata& Ramely, Rosnelifaizur& Sani, Ikhwan& Zakaria, Andee Dzulkarnaen…[et al.]. 2018. Snakehead Consumption Enhances Wound Healing? From Tradition to Modern Clinical Practice: A Prospective Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1154747
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sahid, Nik Amin…[et al.]. Snakehead Consumption Enhances Wound Healing? From Tradition to Modern Clinical Practice: A Prospective Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1154747
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sahid, Nik Amin& Hayati, Firdaus& Rao, Challa Venkata& Ramely, Rosnelifaizur& Sani, Ikhwan& Zakaria, Andee Dzulkarnaen…[et al.]. Snakehead Consumption Enhances Wound Healing? From Tradition to Modern Clinical Practice: A Prospective Randomized Controlled Trial. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1154747
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154747
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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