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In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis
المؤلفون المشاركون
Arulselvan, Palanisamy
Tan, Woan Sean
Norhaizan, Mohd Esa
Gothai, Sivapragasam
Kumar, S. Suresh
Muniandy, Katyakyini
Chandramohan, Govindasamy
Al-Numair, Khalid S.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-02-19
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Impaired wound healing is one of the serious problems among the diabetic patients.
Currently, available treatments are limited due to side effects and cost effectiveness.
In line with that, we attempted to use a natural source to study its potential towards the wound healing process.
Therefore, Alternanthera sessilis (A.
sessilis), an edible and medicinal plant, was chosen as the target sample for the study.
During this investigation, the wound closure properties using stem extract of A.
sessilis were analyzed.
Accordingly, we analyzed the extract on free radical scavenging capacity and the cell migration of two most prominent cell types on the skin, human dermal fibroblast (NHDF), keratinocytes (HaCaT), and diabetic human dermal fibroblast (HDF-D) to mimic the wound healing in diabetic patients.
The bioactive compounds were identified using gas chromatography-mass spectrometry (GC-MS).
We discovered that the analysis exhibited a remarkable antioxidant, proliferative, and migratory rate in NHDF, HaCaT, and HDF-D in dose-dependent manner, which supports wound healing process, due to the presence of wound healing associated phytocompounds such as Hexadecanoic acid.
This study suggested that the stem extract of A.
sessilis might be a potential therapeutic agent for skin wound healing, supporting its traditional medicinal uses.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Muniandy, Katyakyini& Gothai, Sivapragasam& Tan, Woan Sean& Kumar, S. Suresh& Norhaizan, Mohd Esa& Chandramohan, Govindasamy…[et al.]. 2018. In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154777
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Muniandy, Katyakyini…[et al.]. In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1154777
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Muniandy, Katyakyini& Gothai, Sivapragasam& Tan, Woan Sean& Kumar, S. Suresh& Norhaizan, Mohd Esa& Chandramohan, Govindasamy…[et al.]. In Vitro Wound Healing Potential of Stem Extract of Alternanthera sessilis. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1154777
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1154777
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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