In Vitro Effect of Cinnamomum zeylanicum Blume Essential Oil on Candida spp. Involved in Oral Infections
المؤلفون المشاركون
Castellano, Lúcio Roberto
de Aquino, Sabrina Garcia
Lima, Jefferson Muniz de
Rangel, Marianne de Lucena
Castro, Ricardo Dias de
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-10-17
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
The present study demonstrates the antifungal potential of chemically characterized essential oil (EO) of Cinnamomum zeylanicum Blume on Candida spp.
biofilm and establishes its mode of action, effect on fungal growth kinetics, and cytotoxicity to human cells.
The minimal inhibitory concentration (MIC) and minimal fungicidal concentration (MFC) values varied from 62.5 to 1,000 μg/mL, and the effect seems to be due to interference with cell wall biosynthesis.
The kinetics assay showed that EO at MICx2 (500 μg/mL) induced a significant (p < 0.05) reduction of the fungal growth after exposure for 8 h.
At this concentration, the EO was also able to hinder biofilm formation and reduce Candida spp.
monospecies and multispecies in mature biofilm at 24 h and 48 h (p < 0.05).
A protective effect on human red blood cells was detected with the EO at concentrations up to 750 μg/mL, as well as an absence of a significant reduction (p > 0.05) in the viability of human red blood cells at concentrations up to 1,000 μg/mL.
Phytochemical analysis identified eugenol as the main component (68.96%) of the EO.
C.
zeylanicum Blume EO shows antifungal activity, action on the yeast cell wall, and a deleterious effect on Candida spp.
biofilms.
This natural product did not show evidence of cytotoxicity toward human cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rangel, Marianne de Lucena& de Aquino, Sabrina Garcia& Lima, Jefferson Muniz de& Castellano, Lúcio Roberto& Castro, Ricardo Dias de. 2018. In Vitro Effect of Cinnamomum zeylanicum Blume Essential Oil on Candida spp. Involved in Oral Infections. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155063
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rangel, Marianne de Lucena…[et al.]. In Vitro Effect of Cinnamomum zeylanicum Blume Essential Oil on Candida spp. Involved in Oral Infections. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-1155063
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rangel, Marianne de Lucena& de Aquino, Sabrina Garcia& Lima, Jefferson Muniz de& Castellano, Lúcio Roberto& Castro, Ricardo Dias de. In Vitro Effect of Cinnamomum zeylanicum Blume Essential Oil on Candida spp. Involved in Oral Infections. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-13.
https://search.emarefa.net/detail/BIM-1155063
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155063
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر