Multicenter Study of the Hemorrhage Risk after Endoscopic Mucosal Resection Associated with Direct Oral Anticoagulants
المؤلفون المشاركون
Inada, Yutaka
Naito, Yuji
Yasuda, Ritsu
Murakami, Takaaki
Hirose, Ryohei
Inoue, Ken
Dohi, Osamu
Okuda, Takashi
Hasegawa, Daisuke
Okuda, Kotaro
Ogiso, Kiyoshi
Inagaki, Yoshikazu
Tomie, Akira
Soga, Koichi
Itoh, Yoshito
Yoshida, Naohisa
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-18
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Backgrounds and Aims.
Recently, direct oral anticoagulants (DOACs) have become widely used for preventing thromboembolism.
However, postoperative hemorrhage (POH) is a major complication associated with endoscopic mucosal resection (EMR) for colorectal lesions.
In this multicenter study, we analyzed the incidence of POH after EMR associated with DOACs and explored the associated risk factors.
Materials and Methods.
This study was a multicenter retrospective cohort study conducted at 8 Japanese institutions.
A total of 2062 cases that underwent EMR for colorectal lesions at these 8 institutions from October 2016 to September 2017 were analyzed.
The cases were divided into 4 groups: the DOAC group (63 cases), warfarin group (34 cases), antiplatelet group (185 cases), and no antithrombotics group (1780 cases).
In all lesions of the DOAC and warfarin groups, endoscopic clipping was performed after EMR.
The rate of POH in the DOAC group, patients’ clinical characteristics, the risk factors of POH, and the rate of thromboembolism due to stopping DOACs were compared with other groups.
Results.
The rates of POH were 7.9%∗ (5/63), 2.9% (1/34), 3.2% (6/185), and 0.6%∗∗ (11/1780) in the DOAC, warfarin, antiplatelet, and no antithrombotics groups, respectively (∗ vs.
∗∗, p<0.001).
Regarding risk factors, the tumor size with POH (mm) was significantly bigger than that without POH (16.2±8.3 vs.
7.2±4.9, p<0.001).
There were no significant differences in the rates of POH based on the type of DOAC.
In addition, no thromboembolisms occurred due to stopping of DOAC treatment.
Conclusions.
Patients receiving DOACs had significantly higher rates of POH after EMR than those without antithrombotics.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yasuda, Ritsu& Yoshida, Naohisa& Murakami, Takaaki& Hirose, Ryohei& Inoue, Ken& Dohi, Osamu…[et al.]. 2019. Multicenter Study of the Hemorrhage Risk after Endoscopic Mucosal Resection Associated with Direct Oral Anticoagulants. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1155273
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yasuda, Ritsu…[et al.]. Multicenter Study of the Hemorrhage Risk after Endoscopic Mucosal Resection Associated with Direct Oral Anticoagulants. Gastroenterology Research and Practice No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1155273
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yasuda, Ritsu& Yoshida, Naohisa& Murakami, Takaaki& Hirose, Ryohei& Inoue, Ken& Dohi, Osamu…[et al.]. Multicenter Study of the Hemorrhage Risk after Endoscopic Mucosal Resection Associated with Direct Oral Anticoagulants. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1155273
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155273
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر