Digital Gene Expression Profiling Analysis of Aged Mice under Moxibustion Treatment
المؤلفون المشاركون
Jiang, Yunyao
Liu, Nan
Hou, Jincai
Huang, Jian
Xing, Min
Lim, Minyee
Luo, Xue
Zhao, Baixiao
Han, Li
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-02
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Aging is closely connected with death, progressive physiological decline, and increased risk of diseases, such as cancer, arteriosclerosis, heart disease, hypertension, and neurodegenerative diseases.
It is reported that moxibustion can treat more than 300 kinds of diseases including aging related problems and can improve immune function and physiological functions.
The digital gene expression profiling of aged mice with or without moxibustion treatment was investigated and the mechanisms of moxibustion in aged mice were speculated by gene ontology and pathway analysis in the study.
Almost 145 million raw reads were obtained by digital gene expression analysis and about 140 million (96.55%) were clean reads.
Five differentially expressed genes with an adjusted P value < 0.05 and | log 2 ( f o l d c h a n g e ) | > 1 were identified between the control and moxibustion groups.
They were Gm6563, Gm8116, Rps26-ps1, Nat8f4, and Igkv3-12.
Gene ontology analysis was carried out by the GOseq R package and functional annotations of the differentially expressed genes related to translation, mRNA export from nucleus, mRNA transport, nuclear body, acetyltransferase activity, and so on.
Kyoto Encyclopedia of Genes and Genomes database was used for pathway analysis and ribosome was the most significantly enriched pathway term.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Nan& Jiang, Yunyao& Xing, Min& Zhao, Baixiao& Hou, Jincai& Lim, Minyee…[et al.]. 2018. Digital Gene Expression Profiling Analysis of Aged Mice under Moxibustion Treatment. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1155285
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Nan…[et al.]. Digital Gene Expression Profiling Analysis of Aged Mice under Moxibustion Treatment. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1155285
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Nan& Jiang, Yunyao& Xing, Min& Zhao, Baixiao& Hou, Jincai& Lim, Minyee…[et al.]. Digital Gene Expression Profiling Analysis of Aged Mice under Moxibustion Treatment. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1155285
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155285
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر