B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis
المؤلفون المشاركون
Wei, Xin
Yao, Weifeng
Li, Huiping
Qian, Jingjing
Xie, Yaosheng
Zhang, Zhuo
Lu, Hong
Shi, Liang
Lin, Xiangyang
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-06
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
Purpose.
Pancreatitis can lead to systemic inflammatory response, but the relationship between lymphocyte changes and patients with pancreatitis remains unclear.
In this study, we evaluated the feedback function of changes in peripheral lymphocyte subsets on the condition of patients with pancreatitis.
Materials and Methods.
131 acute pancreatitis (AP) patients and 11 chronic pancreatitis (CP) patients constituted the patients’ group; 20 healthy individuals were enrolled as healthy controls (HC).
Serum concentration of C-reactive protein (CRP), amylase, and lipase and the frequency and absolute number of many types of peripheral lymphocytes (including T, B, NK, CD16+/CD56+ T, CD4+ T, CD8+ T, CD4+CD8+ T, and CD4−CD8− T cells) were detected on admission and the seventh day of standard treatment.
Besides, the length of hospital stay was recorded.
Results.
The absolute number of all lymphocytes we studied decreased in patients with CP and in patients with almost all types of AP.
The frequency change of lymphocytes varies among the different types of AP.
During disease onset, B cell frequency correlated positively with CRP concentration and NK cell frequency correlated positively with amylase and lipase concentration.
B cell frequency and CD4+ T cell absolute number were recovering towards normal after short-term treatment.
The frequency of B cells and NK cells correlated positively with the length of hospital stay.
Conclusions.
B cells and NK cells closely correlate with patients’ condition and may help to diagnose AP more accurately and reflect treatment effect of AP in time, affecting the recovery speed of patients with M-AP, which may help physicians to better understand the pathophysiology of pancreatitis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wei, Xin& Yao, Weifeng& Li, Huiping& Qian, Jingjing& Xie, Yaosheng& Zhang, Zhuo…[et al.]. 2019. B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis. Gastroenterology Research and Practice،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1155420
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wei, Xin…[et al.]. B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis. Gastroenterology Research and Practice No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1155420
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wei, Xin& Yao, Weifeng& Li, Huiping& Qian, Jingjing& Xie, Yaosheng& Zhang, Zhuo…[et al.]. B and NK Cells Closely Correlate with the Condition of Patients with Acute Pancreatitis. Gastroenterology Research and Practice. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1155420
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155420
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر