Group B Streptococcus (GBS) Colonization and Disease among Pregnant Women: A Historical Cohort Study
المؤلفون المشاركون
Swamy, Geeta K.
Edwards, James M.
Watson, Nora
Focht, Chris
Wynn, Clara
Todd, Christopher A.
Walter, Emmanuel B.
Heine, R. Phillips
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Maternal GBS colonization is associated with early-onset neonatal sepsis and extensive efforts are directed to preventing this complication.
Less is known about maternal risks of GBS colonization.
We seek to provide a modern estimate of the incidence and impact of maternal GBS colonization and invasive GBS disease.
Methods.
A single center historical cohort study of all births between 2003 and 2015 was performed.
Data was collected via electronic health record abstraction using an institutional specific tool.
Descriptive statistics were performed regarding GBS status.
Inferential statistics were performed comparing risk of adverse pregnancy outcomes in cohorts with and without GBS colonization as well as cohorts with GBS colonization and invasive GBS disease.
Results.
A total of 60,029 deliveries were included for analysis.
Overall, 21.6% of the population was GBS colonized and 0.1% had invasive GBS disease.
GBS colonization was associated with younger maternal age, Black race, non-Hispanic ethnicity, chronic hypertension, preexisting diabetes, and tobacco use (p<0.01).
In the adjusted analyses, there was an increased risk of gestational diabetes (aRR 1.21, 95% CI 1.11-1.32) in colonized pregnancies and a decreased incidence of short cervix (aRR 0.64, 95% CI 0.52-0.79), chorioamnionitis (aRR 0.76, 95% CI 0.66-0.87), wound infection (aRR 0.75, 95% CI 0.64-0.88), and operative delivery (aRR 0.85, 95% CI 0.83-0.88).
Conclusions.
This modern-day large cohort of all births over a 12-year period demonstrates a GBS colonization rate of 21.6%.
This data reflects a need to assess maternal and perinatal outcomes in addition to neonatal GBS sepsis rates to inform decisions regarding the utility of maternal vaccination.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Edwards, James M.& Watson, Nora& Focht, Chris& Wynn, Clara& Todd, Christopher A.& Walter, Emmanuel B.…[et al.]. 2019. Group B Streptococcus (GBS) Colonization and Disease among Pregnant Women: A Historical Cohort Study. Infectious Diseases in Obstetrics and Gynecology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1155700
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Edwards, James M.…[et al.]. Group B Streptococcus (GBS) Colonization and Disease among Pregnant Women: A Historical Cohort Study. Infectious Diseases in Obstetrics and Gynecology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1155700
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Edwards, James M.& Watson, Nora& Focht, Chris& Wynn, Clara& Todd, Christopher A.& Walter, Emmanuel B.…[et al.]. Group B Streptococcus (GBS) Colonization and Disease among Pregnant Women: A Historical Cohort Study. Infectious Diseases in Obstetrics and Gynecology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1155700
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155700
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر