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The Effect of Volatile Oil from Vernonia anthelmintica Seeds on Melanin Synthesis in B16 Cells and Its Chemical Analysis by GC-QTOF-MS
المؤلفون المشاركون
Aobuli, Abulikemu
Maitusong, Jumai
Bakri, Mahinur
Lu, Xueying
Maiwulanjiang, Maitinuer
Aisa, Haji A.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-08-07
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Vernonia anthelmintica Willd.
seeds have been used in folk medicine for the treatment of leukoderma in Xinjiang, China, for more than 300 years.
The promoting activities of its volatile oil (AVO) in melanogenesis and its chemical composition were investigated in this paper.
The bioactivities of AVO were examined by melanin synthesis and tyrosinase activity assay in B16 cells.
Using GC-QTOF-MS technology, each compound of AVO contains a single separated peak in GC and the retention indices of every GC peak were calculated by the retention times of C7~C30 n-alkanes that were injected at the same chromatographic conditions.
Then each individual peak was identified by comparing its mass spectrum with the MS library (NIST 14).
As a result, AVO increased the melanin content and tyrosinase activity in a dose-dependent manner at concentrations of 10-30μg·mL−1.
The 64 compounds were identified in AVO which occupied 95.15% of total peak area in GC.
They mainly contained caryophyllene (23.73%), sabinene (18.15%), α-thujene (6.57%), thymol (5.29%), 4-epi-α-acoradiene (4.98%), limonene (4.92%), anethole (3.44%), etc.
According to the results the AVO can promote melanogenesis and upregulate tyrosinase activity in B16 cells.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Aobuli, Abulikemu& Maitusong, Jumai& Bakri, Mahinur& Lu, Xueying& Maiwulanjiang, Maitinuer& Aisa, Haji A.. 2018. The Effect of Volatile Oil from Vernonia anthelmintica Seeds on Melanin Synthesis in B16 Cells and Its Chemical Analysis by GC-QTOF-MS. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1155832
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Aobuli, Abulikemu…[et al.]. The Effect of Volatile Oil from Vernonia anthelmintica Seeds on Melanin Synthesis in B16 Cells and Its Chemical Analysis by GC-QTOF-MS. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1155832
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Aobuli, Abulikemu& Maitusong, Jumai& Bakri, Mahinur& Lu, Xueying& Maiwulanjiang, Maitinuer& Aisa, Haji A.. The Effect of Volatile Oil from Vernonia anthelmintica Seeds on Melanin Synthesis in B16 Cells and Its Chemical Analysis by GC-QTOF-MS. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1155832
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155832
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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