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Investigation of Acid-Base Indicator Property of Plumbagin from Plumbago zeylanica Linn
المؤلفون المشاركون
Adusei, Emmanuel B. A.
Adosraku, Reimmel K.
Oppong-Kyekyeku, James
Amengor, Cedric D. K.
المصدر
International Journal of Analytical Chemistry
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-08-18
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
There has been an increasing interest in the search for colour indicators of natural origin for titrimetric analysis.
This is due to some challenges associated with the currently used synthetic ones.
This study evaluates and validates the acid-base indicator property of plumbagin isolated from Plumbago zeylanica Linn.
Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) was isolated from the roots of Plumbago zeylanica Linn using silica gel chromatography and characterized using spectroscopic methods in comparison with those reported in the literature.
Its acid-base indicator property was evaluated alongside phenolphthalein and methyl orange, after it was found to exhibit a sharp change in colour at various pH ranges.
The plumbagin indicator was successfully used to assay ibuprofen powder and tablets (400 mg) using the British Pharmacopoeia (2013) method.
Data obtained were analyzed statistically by Student’s t-test and one-way ANOVA in GraphPad Prism (version 5.01, 2010).
Analysis of the use of the plumbagin indicator in acid-base titrations between strong acids and strong bases and between weak acids and strong bases has been evaluated and validated according to the ICH guidelines.
Plumbagin use in ibuprofen powder and tablets has also been verified.
Plumbagin has been validated for use as an indicator suitable for different acid-base titrations and the analysis of ibuprofen.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Adusei, Emmanuel B. A.& Adosraku, Reimmel K.& Oppong-Kyekyeku, James& Amengor, Cedric D. K.. 2019. Investigation of Acid-Base Indicator Property of Plumbagin from Plumbago zeylanica Linn. International Journal of Analytical Chemistry،Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1155878
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Adusei, Emmanuel B. A.…[et al.]. Investigation of Acid-Base Indicator Property of Plumbagin from Plumbago zeylanica Linn. International Journal of Analytical Chemistry No. 2019 (2019), pp.1-13.
https://search.emarefa.net/detail/BIM-1155878
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Adusei, Emmanuel B. A.& Adosraku, Reimmel K.& Oppong-Kyekyeku, James& Amengor, Cedric D. K.. Investigation of Acid-Base Indicator Property of Plumbagin from Plumbago zeylanica Linn. International Journal of Analytical Chemistry. 2019. Vol. 2019, no. 2019, pp.1-13.
https://search.emarefa.net/detail/BIM-1155878
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1155878
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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