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Extramural Venous Invasion as Prognostic Factor of Recurrence in Stage 1 and 2 Colon Cancer
المؤلفون المشاركون
Loffeld, Ruud J. L. F.
van Eeghen, E. E.
Flens, M. J.
Mulder, M. M. R.
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-28
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
Extramural venous invasion (EMVI) is a prognostic indicator in patients with colorectal cancer.
However, its additional value in patients with stage 1 and 2 colorectal cancer is uncertain.
In the present study, the incidence of EMVI and the hazard ratio for recurrence in patients with stage 1 and 2 colon cancer were studied.
Methods.
184 patients treated for stage 1 and 2 colon cancer were included with a follow-up of at least 5 years.
Chart review was performed and EMVI was assessed by two separate pathologists.
EMVI was scored with additional caldesmon staining on the resection specimen.
Primary outcomes were recurrence-free survival (RFS) measured through the Cox regression analysis and prevalence of EMVI.
Results.
There were 10 cases of EMVI and 3 cases of intramural venous invasion (IMVI) all occurring in patients with stage 2 disease corresponding to a prevalence of 9%.
Thirty-one percent of the patients with venous invasion experienced recurrence versus 14% in patients without, corresponding with a hazard ratio of 2.39 (p=0.11).
Conclusion.
The present study demonstrates a trend towards an increased risk of recurrence in patients with stage 2 colon cancer with venous invasion.
This warrants consideration of adjuvant chemotherapy despite the lack of lymph node metastases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
van Eeghen, E. E.& Flens, M. J.& Mulder, M. M. R.& Loffeld, Ruud J. L. F.. 2017. Extramural Venous Invasion as Prognostic Factor of Recurrence in Stage 1 and 2 Colon Cancer. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1156156
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
van Eeghen, E. E.…[et al.]. Extramural Venous Invasion as Prognostic Factor of Recurrence in Stage 1 and 2 Colon Cancer. Gastroenterology Research and Practice No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1156156
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
van Eeghen, E. E.& Flens, M. J.& Mulder, M. M. R.& Loffeld, Ruud J. L. F.. Extramural Venous Invasion as Prognostic Factor of Recurrence in Stage 1 and 2 Colon Cancer. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1156156
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156156
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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