Inflammatory Markers as Prognostic Factors of Survival in Patients Affected by Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization
المؤلفون المشاركون
Mosca, Stefano
Brunese, Luca
Rebonato, A.
Graziosi, L.
Maiettini, D.
Marino, E.
De Angelis, V.
Rossi, M.
Orgera, G.
Scialpi, M.
Donini, A.
Metro, G.
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-15
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Introduction.
Transarterial chemoembolization (TACE) is a good choice for hepatocellular carcinoma (HCC) treatment when surgery and liver transplantation are not feasible.
Few studies reported the value of prognostic factors influencing survival after chemoembolization.
In this study, we evaluated whether preoperative inflammatory factors such as neutrophil to lymphocyte ratio and platelet to lymphocyte ratio affected our patient survival when affected by hepatocellular carcinoma.
Methods.
We retrospectively evaluated a total of 72 patients with hepatocellular carcinoma that underwent TACE.
We enrolled patients with different etiopathogeneses of hepatitis and histologically proven HCC not suitable for surgery.
The overall study population was dichotomized in two groups according to the median NLR value and was analyzed also according to other prognostic factors.
Results.
The global median overall survival (OS) was 28 months.
The OS in patients with high NLR was statistically significantly shorter than that in patients with low NLR.
The following pretreatment variables were significantly associated with the OS in univariate analyses: age, Child-Pugh score, BCLC stage, INR, and NLR.
Pretreated high NLR was an independently unfavorable factor for OS.
Conclusion.
NLR could be considered a good prognostic factor of survival useful to stratify patients that could benefit from TACE treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rebonato, A.& Graziosi, L.& Maiettini, D.& Marino, E.& De Angelis, V.& Brunese, Luca…[et al.]. 2017. Inflammatory Markers as Prognostic Factors of Survival in Patients Affected by Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156372
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rebonato, A.…[et al.]. Inflammatory Markers as Prognostic Factors of Survival in Patients Affected by Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization. Gastroenterology Research and Practice No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1156372
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rebonato, A.& Graziosi, L.& Maiettini, D.& Marino, E.& De Angelis, V.& Brunese, Luca…[et al.]. Inflammatory Markers as Prognostic Factors of Survival in Patients Affected by Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156372
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156372
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر