Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy
المؤلفون المشاركون
Nie, Run-Cong
Zhou, Zhi-Wei
Li, Yuan-Fang
Chen, Shi
Ou-Yang, Li-Ying
Xiang, Jun
Chen, Ying-Bo
Peng, Jun-Sheng
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Aim .
To investigate whether tumor size is a reasonable indication for adjuvant chemotherapy for T3-4aN0M0 gastric cancer patients after D2 gastrectomy.
Method.
We performed a retrospective study of 269 patients with a histological diagnosis of T3-4aN0M0 stage gastric cancer who underwent D2 radical surgery at the Sun Yat-sen University Cancer Center or the Sixth Affiliated Hospital of Sun Yat-sen University between January 2006 and December 2010.
The follow-up lasted until June of 2015.
Chi-square tests and Kaplan-Meier methods were employed to compare the clinicopathological variables and prognoses.
Result.
For this group of patients, univariate analyses revealed that tumor size (p<0.001), pathological T stage (p<0.001), and tumor location (p=0.025) were significant prognostic factors.
Adjuvant chemotherapy did not exhibit prognostic benefits.
For patients with tumors larger than 5 cm, univariate analysis revealed that tumor location (p=0.007), Borrmann type (p=0.039), postoperative chemotherapy (p=0.003), and pathological T stage (p<0.001) were significant prognostic factors.
Multivariate analysis revealed that postoperative chemotherapy and pathological T stage were independent prognostic factors.
Conclusion.
Our results imply that tumor size should be a critical factor in the decision to utilize adjuvant chemotherapy for T3-4aN0M0 gastric cancer patients after D2 gastrectomy.
Additional randomized controlled trials are required before this conclusion can be considered definitive.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Shi& Ou-Yang, Li-Ying& Nie, Run-Cong& Li, Yuan-Fang& Xiang, Jun& Zhou, Zhi-Wei…[et al.]. 2017. Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156422
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Shi…[et al.]. Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy. Gastroenterology Research and Practice No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1156422
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Shi& Ou-Yang, Li-Ying& Nie, Run-Cong& Li, Yuan-Fang& Xiang, Jun& Zhou, Zhi-Wei…[et al.]. Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156422
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156422
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر