![](/images/graphics-bg.png)
Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy
المؤلفون المشاركون
Nie, Run-Cong
Zhou, Zhi-Wei
Li, Yuan-Fang
Chen, Shi
Ou-Yang, Li-Ying
Xiang, Jun
Chen, Ying-Bo
Peng, Jun-Sheng
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-26
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Aim .
To investigate whether tumor size is a reasonable indication for adjuvant chemotherapy for T3-4aN0M0 gastric cancer patients after D2 gastrectomy.
Method.
We performed a retrospective study of 269 patients with a histological diagnosis of T3-4aN0M0 stage gastric cancer who underwent D2 radical surgery at the Sun Yat-sen University Cancer Center or the Sixth Affiliated Hospital of Sun Yat-sen University between January 2006 and December 2010.
The follow-up lasted until June of 2015.
Chi-square tests and Kaplan-Meier methods were employed to compare the clinicopathological variables and prognoses.
Result.
For this group of patients, univariate analyses revealed that tumor size (p<0.001), pathological T stage (p<0.001), and tumor location (p=0.025) were significant prognostic factors.
Adjuvant chemotherapy did not exhibit prognostic benefits.
For patients with tumors larger than 5 cm, univariate analysis revealed that tumor location (p=0.007), Borrmann type (p=0.039), postoperative chemotherapy (p=0.003), and pathological T stage (p<0.001) were significant prognostic factors.
Multivariate analysis revealed that postoperative chemotherapy and pathological T stage were independent prognostic factors.
Conclusion.
Our results imply that tumor size should be a critical factor in the decision to utilize adjuvant chemotherapy for T3-4aN0M0 gastric cancer patients after D2 gastrectomy.
Additional randomized controlled trials are required before this conclusion can be considered definitive.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Shi& Ou-Yang, Li-Ying& Nie, Run-Cong& Li, Yuan-Fang& Xiang, Jun& Zhou, Zhi-Wei…[et al.]. 2017. Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156422
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Shi…[et al.]. Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy. Gastroenterology Research and Practice No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1156422
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Shi& Ou-Yang, Li-Ying& Nie, Run-Cong& Li, Yuan-Fang& Xiang, Jun& Zhou, Zhi-Wei…[et al.]. Tumor Size Is a Critical Factor in Adjuvant Chemotherapy for T3-4aN0M0 Gastric Cancer Patients after D2 Gastrectomy. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1156422
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156422
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)