Effects of Different Processed Products of Polygonum multiflorum on the Liver
المؤلفون المشاركون
Li, Ruo-Lan
Gao, Feng
Yan, Shu-Ting
Ou, Li
Li, Ming
Chen, Lin
Wei, Pei-Feng
Gao, Zong-Qiang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-09
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Objective.
Based on in vitro and in vivo experimental studies, the changes of the main components of Polygonum multiflorum and different processed products and their effects on hepatotoxicity were investigated.
Methods.
The components of different processed products of Polygonum multiflorum were determined by HPLC.
The effects of processed products of different processing time periods on HepG2 cells were detected by using cell count kit-8 and the apoptosis method; the effects of different processed products on the mouse liver were detected by reverse transcription polymerase chain reaction and immunohistochemistry.
Results.
With the extension of processing time, the contents of various chemical components in Polygonum multiflorum increased, while the content of stilbene glucoside decreased.
The serum of Polygonum multiflorum group and different steaming time groups had obvious inhibitory effect on HepG2 cells.
For normal mice, the toxicity of raw Polygonum multiflorum and processed products at different processing time periods had certain toxicity to liver and gradually decreased with the prolongation of processing time.
For mice in the liver injury group, the therapeutic effect of raw Polygonum multiflorum and processed products at different processing time periods was not obvious, but there is a trend of treatment.
Conclusion.
The content of the main components in Radix Polygonum multiflorum can be affected by processing time; stilbene glycoside may be the main component leading to liver injury.
The degree of liver injury caused by Radix Polygonum multiflorum is negatively correlated with processing time.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Ruo-Lan& Gao, Feng& Yan, Shu-Ting& Ou, Li& Li, Ming& Chen, Lin…[et al.]. 2020. Effects of Different Processed Products of Polygonum multiflorum on the Liver. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1156474
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Ruo-Lan…[et al.]. Effects of Different Processed Products of Polygonum multiflorum on the Liver. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1156474
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Ruo-Lan& Gao, Feng& Yan, Shu-Ting& Ou, Li& Li, Ming& Chen, Lin…[et al.]. Effects of Different Processed Products of Polygonum multiflorum on the Liver. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1156474
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156474
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر