Gastroprotective Value of Berries: Evidences from Methanolic Extracts of Morus nigra and Rubus niveus Fruits
المؤلفون المشاركون
Campos, Adriana
da Silva, Luisa Mota
Faloni de Andrade, Sérgio
Nesello, Luciane Angela Nottar
Beleza, Maria Luisa Maes Lima
Mariot, Marihá
Mariano, Luísa Nathália Bolda
de Souza, Priscila
Cechinel Filho, Valdir
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-09-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
This study evaluated the gastroprotective value of the methanol extracts from fruits of Morus nigra L.
(black mulberry (MEMN)) and Rubus niveus Thunb (raspberry (MERN)).
The total phenolic compounds and flavonoids were measured, as well as the in vitro 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenger activity.
The gastroprotective effects of the extracts against 60% ethanol/0.3 M HCl were evaluated in mice.
After that, the lipid hydroperoxides and reduced glutathione levels at ulcerated tissue were determined.
The effects of extracts on H+/K+-ATPase activity were also verified.
The extracts exhibited high contents of polyphenols; however, MERN presented 1.5-fold higher levels.
The presence of flavonoids also was confirmed.
In addition, MEMN (IC50 = 13.74 μg/mL) and MERN (IC50 = 14.97 μg/mL) scavenged DPPH radical.
The MEMN reduced the ulcer area only at 300 mg/kg (p.o.) by 64.06%.
Interestingly, MERN decreased the ulcer area in a superior potency (ED50 = 20.88 mg/kg), reducing the ulcer area by 81.86% at 300 mg/kg, and increased the gastric mucin levels.
The antioxidant effects of extracts were evidenced by reduced lipoperoxides and increased reduction of glutathione amount in the gastric mucosa.
However, MEMN or MERN did not change the H+/K+-ATPase activity.
These results confirm that M.
nigra and R.
niveus are berries with a gastroprotective value by strengthening of gastric protective factors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nesello, Luciane Angela Nottar& Beleza, Maria Luisa Maes Lima& Mariot, Marihá& Mariano, Luísa Nathália Bolda& de Souza, Priscila& Campos, Adriana…[et al.]. 2017. Gastroprotective Value of Berries: Evidences from Methanolic Extracts of Morus nigra and Rubus niveus Fruits. Gastroenterology Research and Practice،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156563
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nesello, Luciane Angela Nottar…[et al.]. Gastroprotective Value of Berries: Evidences from Methanolic Extracts of Morus nigra and Rubus niveus Fruits. Gastroenterology Research and Practice No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1156563
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nesello, Luciane Angela Nottar& Beleza, Maria Luisa Maes Lima& Mariot, Marihá& Mariano, Luísa Nathália Bolda& de Souza, Priscila& Campos, Adriana…[et al.]. Gastroprotective Value of Berries: Evidences from Methanolic Extracts of Morus nigra and Rubus niveus Fruits. Gastroenterology Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1156563
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156563
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر