![](/images/graphics-bg.png)
Aidi Injection, Compound Kushen Injection, or Kanglaite Injection: Which Is the Best Partner with Systemic Chemotherapy for Patients with HCC? A Network Meta-Analysis
المؤلفون المشاركون
Zhong, Xiang-Gen
Dou, Dou
Zhang, Ze-yu
Wu, Zhi-yuan
Qiu, Xu-dong
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-21
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Objective.
The aim of this network meta-analysis (NMA) was to explore the effectiveness of different traditional Chinese medicine injections (TCMIs) combined with systemic chemotherapy for the treatment of hepatocellular carcinoma (HCC).
Methods.
A comprehensive search for randomized controlled trials (RCTs) was performed with regard to different TCMIs for treating HCC in seven electronic databases up to November 2019.
The quality assessment of the included RCTs was conducted according to the Cochrane risk of bias tool.
The objective response rate (ORR), clinical benefit rate (CBR), and Karnofsky performance score (KPS) data were extracted.
The network meta-analysis used the network package in Stata software to analyse the data and draw a map of the evidence summarizing the direct and indirect comparisons.
Results.
A total of 1697 articles were retrieved through the comprehensive search.
Twenty RCTs focusing on Aidi injection, compound Kushen injection, and Kanglaite injection as adjuvant therapies to chemotherapy were included, involving a total of 1418 patients.
The NMA statistics showed that all three indicators (ORR, CBR, and KPS) were better in the combined treatment group of TCMIs with chemotherapy than that in the single treatment group of chemotherapy alone.
Kanglaite injection tended to be better than the other two in terms of primary outcome, but there was not a significant difference.
The combined treatment group had fewer adverse reactions than the single treatment group.
Moreover, several articles reported that TCMIs combined with chemotherapy could increase the number of CD3+ and CD4+ T lymphocytes and the ratio of CD4+/CD8+ T lymphocytes.
Conclusions.
TCMIs combined with systemic chemotherapy could be an effective and safe treatment option for patients with HCC.
Kanglaite injection showed a tendency to be better than the other two kinds of injections in terms of ORR.
Nevertheless, additional results from multicentre trials and high-quality studies will be pivotal for supporting our findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dou, Dou& Zhang, Ze-yu& Wu, Zhi-yuan& Qiu, Xu-dong& Zhong, Xiang-Gen. 2020. Aidi Injection, Compound Kushen Injection, or Kanglaite Injection: Which Is the Best Partner with Systemic Chemotherapy for Patients with HCC? A Network Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1156594
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dou, Dou…[et al.]. Aidi Injection, Compound Kushen Injection, or Kanglaite Injection: Which Is the Best Partner with Systemic Chemotherapy for Patients with HCC? A Network Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1156594
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dou, Dou& Zhang, Ze-yu& Wu, Zhi-yuan& Qiu, Xu-dong& Zhong, Xiang-Gen. Aidi Injection, Compound Kushen Injection, or Kanglaite Injection: Which Is the Best Partner with Systemic Chemotherapy for Patients with HCC? A Network Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1156594
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156594
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)