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Acupuncture for Cancer-Induced Bone Pain in Animal Models: A Systemic Review and Meta-Analysis
المؤلفون المشاركون
Lu, Sheng-feng
Fu, Shu-ping
Yu, Mei-ling
Qian, Jia-jia
Chen, Jia-ying
Zheng, Yu-wen
Lu, Zhi-gang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-14، 14ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-30
دولة النشر
مصر
عدد الصفحات
14
التخصصات الرئيسية
الملخص EN
Background.
Cancer-induced bone pain (CIBP) is a highly prevalent symptom, which afflicts vast majority of patients who suffer from cancer.
The current treatment options failed to achieve satisfactory effect and the side effects were prominent.
Recent randomized controlled trials (RCTs) of animal demonstrate the benefit of acupuncture for CIBP.
We sought to determine if the pooled data from available RCTs supports the use of acupuncture for CIBP.
Methods.
A literature search for randomized controlled trials was conducted in six electronic databases from inception to May 31, 2019.
Meta-analysis was performed with Review Manager 5.3 software; the publication bias was assessed by Stata 12.0 software.
We used random effects model for pooling data because heterogeneity is absolute among studies to some extent.
Results.
Twenty-four trials were included in the review, of which 12 trials provided detailed data for meta-analyses.
Preliminary evidence indicates that compared to wait list/sham group, acupuncture was effective on increasing paw withdrawal threshold (PWT) and paw withdrawal latency (PWL).
Compared to medicine, acupuncture was less effective on PWT, but as effective as medicine on PWL.
Acupuncture can reinforce medicine’s effect on PWT and PWL.
Compared to the control group, acupuncture was superior to increase body weight (BW), decrease spinal cord glial fibrillary acidic protein (GFAP), and interleukin-1β (IL-1β).
Furthermore, some studies showed acupuncture delay or partially reverse morphine tolerance.
Three studies found acupuncture has no effect on PWT, but 2 of them found acupuncture could enhance small dose of Celebrex’s effect on CIBP.
Conclusions.
Acupuncture was superior to wait list/sham acupuncture on increasing PWT and has no less effect on increasing PWL compared to medicine; acupuncture improved the efficacy of drugs, increased the CIBP animals’ body weight, and decreased their spinal cord GFAP and IL-1β.
High-quality studies are necessary to confirm the results.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yu, Mei-ling& Qian, Jia-jia& Fu, Shu-ping& Chen, Jia-ying& Zheng, Yu-wen& Lu, Zhi-gang…[et al.]. 2020. Acupuncture for Cancer-Induced Bone Pain in Animal Models: A Systemic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1156621
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yu, Mei-ling…[et al.]. Acupuncture for Cancer-Induced Bone Pain in Animal Models: A Systemic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-14.
https://search.emarefa.net/detail/BIM-1156621
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yu, Mei-ling& Qian, Jia-jia& Fu, Shu-ping& Chen, Jia-ying& Zheng, Yu-wen& Lu, Zhi-gang…[et al.]. Acupuncture for Cancer-Induced Bone Pain in Animal Models: A Systemic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-14.
https://search.emarefa.net/detail/BIM-1156621
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156621
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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