A Pilot Study on Characteristics of Metabolomics and Lipidomics according to Sasang Constitution
المؤلفون المشاركون
Kim, Min Jung
Ha, Tae Youl
Do, Eunju
Lee, Da-Hye
Jang, Young Jin
Ahn, Jiyun
Jung, Chang Hwa
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-05-30
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Although classification of an individual’s Sasang constitution is a key step in the prescription of traditional Korean medicine, the classifying process is complex and not objective.
Identification of metabolic-based biomarkers could allow the development of a reliable and sensitive classification technique and even therapeutic management.
Our pilot study investigated whether metabolites in plasma are characteristic of Sasang constitutions.
Ultra-high-performance liquid chromatography-quadrupole time-of-flight mass spectrometry-based metabolic analysis was conducted against 15 Soyangin (SY), 15 Taeeumin (TE), and 18 Soeumin (SE) individuals, as classified according to the Questionnaire for Sasang Constitution Classification II (QSCC II) and specialist diagnosis.
Metabolomics data showed that the TE group was significantly separated from the SY and SE groups.
Nine canonical pathways related to constitution; phenylalanine metabolism, aminoacyl-tRNA, tyrosine, and tryptophan biosynthesis were activated in the TE group as compared with the other groups.
Similar to the results of the metabolomics analysis, the TE group was also significantly separated from the other two groups by lipidomic analysis.
On the other hand, the intensity of lipid metabolites was higher in the SY group than in the other groups.
Our findings suggest that the combined analysis of metabolomics and lipidomics can provide useful information for characteristics of Sasang constitutions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kim, Min Jung& Lee, Da-Hye& Ahn, Jiyun& Ha, Tae Youl& Jang, Young Jin& Do, Eunju…[et al.]. 2018. A Pilot Study on Characteristics of Metabolomics and Lipidomics according to Sasang Constitution. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156838
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kim, Min Jung…[et al.]. A Pilot Study on Characteristics of Metabolomics and Lipidomics according to Sasang Constitution. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-12.
https://search.emarefa.net/detail/BIM-1156838
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kim, Min Jung& Lee, Da-Hye& Ahn, Jiyun& Ha, Tae Youl& Jang, Young Jin& Do, Eunju…[et al.]. A Pilot Study on Characteristics of Metabolomics and Lipidomics according to Sasang Constitution. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-12.
https://search.emarefa.net/detail/BIM-1156838
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156838
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر