Effect of Moxibustion on Inflammatory Cytokines in Animals with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis
المؤلفون المشاركون
Zhong, Yu-mei
Cheng, Bo-
Zhang, Lin-lin
Lu, Wen-ting
Shang, Ya-nan
Zhou, Hai-yan
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-08
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Background.
This study aims to systematically evaluate the effect of moxibustion on the level of inflammatory cytokines in animal models with rheumatoid arthritis (RA) and to provide evidence for the clinical application of moxibustion to the treatment of RA and related basic researches.
Methods.
The databases employed in this study include PubMed, EMBASE, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), SinoMed, and Wanfang Data Information Site.
The retrieval time was from the establishment of these databases to March 2020.
The reviewers made use of the CAMARADES 10-item checklist to evaluate the quality of each included study.
The inflammatory cytokines were considered as the outcome measure.
The Revman 5.3 software was used to conduct meta-analysis on the outcome indicators of the studies included.
Results.
A total of 648 articles were retrieved and 18 animal experiments were included in this study.
The quality scores of the studies ranged from two to eight with a mean of 5.8.
Compared with the effect of the control group, moxibustion reduced the expression of TNF-α (SMD 2.95, 95% CI: 1.99–3.92, P<0.00001), IL-1β (SMD 4.10, 95% CI: 2.37–5.84, P<0.00001), IFN-γ (MD 25, 95% CI: 16.17–33.82, P<0.00001), IL-6 (MD 11.83, 95% CI: 6.22–17.44, P<0.0001), and IL-17 (MD 99.3, 95% CI: 86.83–111.76, P<0.00001).
At the same time, the level of IL-2 (SMD 8.89, 95% CI: 0.93–16.86, P=0.03), IL-4 (MD 1.79, 95% CI: 0.26–3.32, P=0.02), and IL-10 (MD 5.93, 95% CI: 1.37–10.49, P=0.01) increased after moxibustion treatment.
Asymmetric funnel plots indicated that there was publication bias.
Conclusion.
The findings of the present review indicate that moxibustion can protect the synovium of joint in animal models with RA by upregulation of the level of anti-inflammatory cytokines and downregulation of the level of proinflammatory cytokines.
Moxibustion has the potential to relieve inflammation of RA.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhong, Yu-mei& Cheng, Bo-& Zhang, Lin-lin& Lu, Wen-ting& Shang, Ya-nan& Zhou, Hai-yan. 2020. Effect of Moxibustion on Inflammatory Cytokines in Animals with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1156857
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhong, Yu-mei…[et al.]. Effect of Moxibustion on Inflammatory Cytokines in Animals with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-12.
https://search.emarefa.net/detail/BIM-1156857
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhong, Yu-mei& Cheng, Bo-& Zhang, Lin-lin& Lu, Wen-ting& Shang, Ya-nan& Zhou, Hai-yan. Effect of Moxibustion on Inflammatory Cytokines in Animals with Rheumatoid Arthritis: A Systematic Review and Meta-Analysis. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-12.
https://search.emarefa.net/detail/BIM-1156857
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156857
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر