Moroccan Propolis: A Natural Antioxidant, Antibacterial, and Antibiofilm against Staphylococcus aureus with No Induction of Resistance after Continuous Exposure
المؤلفون المشاركون
Popova, Milena
Badiaa, Lyoussi
El-Guendouz, Soukaïna
Aazza, Smail
Neto, Luís
Faleiro, Maria Leonor
Bankova, Vassya
Miguel, M. Graça
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-19، 19ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-12
دولة النشر
مصر
عدد الصفحات
19
التخصصات الرئيسية
الملخص EN
This study was performed to evaluate the total phenols, flavonoids, and antioxidant activities of twenty-four propolis samples from different regions of Morocco.
In addition, two samples were screened regarding the antibacterial effect against four Staphylococcus aureus strains.
Gas chromatography coupled to mass spectra (GC-MS) analysis was done for propolis samples used in antibacterial tests.
The minimum inhibitory and minimum bactericidal concentration (MIC, MBC) were determined.
The potential to acquire the resistance after sequential exposure of bacterial strains and the impact of adaptation to propolis on virulence using the Galleria mellonella were evaluated.
Additionally, the effects of propolis extract on the bacterial adherence ability and its ability to inhibit the quorum sensing activity were also examined.
Among the twenty-four extracts studied, the samples from Sefrou, Outat el Haj, and the two samples marketed in Morocco were the best for scavenging DPPH, ABTS, NO, peroxyl, and superoxide radicals as well as in scavenging of hydrogen peroxide.
A strong correlation was found between the amounts of phenols, flavonoids, and antioxidant activities.
Propolis extract at the MIC value (0.36 mg/mL) significantly reduced (p < 0.001) the virulence potential of S.
aureus ATCC 6538 and the MRSA strains without leading to the development of resistance in the sequence of continuous exposure.
It was able to impair the bacterial biofilm formation.
The results have revealed that sample 1 reduces violacein production in a concentration dependent manner, indicating inhibition of quorum sensing.
This extract has as main group of secondary metabolites flavonoids (31.9%), diterpenes (21.5%), and phenolic acid esters (16.5%).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
El-Guendouz, Soukaïna& Aazza, Smail& Badiaa, Lyoussi& Bankova, Vassya& Popova, Milena& Neto, Luís…[et al.]. 2018. Moroccan Propolis: A Natural Antioxidant, Antibacterial, and Antibiofilm against Staphylococcus aureus with No Induction of Resistance after Continuous Exposure. Evidence-Based Complementary and Alternative Medicine،Vol. 2018, no. 2018, pp.1-19.
https://search.emarefa.net/detail/BIM-1156966
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
El-Guendouz, Soukaïna…[et al.]. Moroccan Propolis: A Natural Antioxidant, Antibacterial, and Antibiofilm against Staphylococcus aureus with No Induction of Resistance after Continuous Exposure. Evidence-Based Complementary and Alternative Medicine No. 2018 (2018), pp.1-19.
https://search.emarefa.net/detail/BIM-1156966
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
El-Guendouz, Soukaïna& Aazza, Smail& Badiaa, Lyoussi& Bankova, Vassya& Popova, Milena& Neto, Luís…[et al.]. Moroccan Propolis: A Natural Antioxidant, Antibacterial, and Antibiofilm against Staphylococcus aureus with No Induction of Resistance after Continuous Exposure. Evidence-Based Complementary and Alternative Medicine. 2018. Vol. 2018, no. 2018, pp.1-19.
https://search.emarefa.net/detail/BIM-1156966
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1156966
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر