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Phenolic Profile of Nipa Palm Vinegar and Evaluation of Its Antilipidemic Activities
المؤلفون المشاركون
Chatatikun, Moragot
Kwanhian, Wiyada
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-09-04
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Obesity and overweight are strongly associated with dyslipidemia which can promote the development of cardiovascular diseases.
Recently, natural products have been suggested as alternative compounds for antioxidant and antilipidemic activity.
The objective of this study was to determine the phenolic compounds and assess the inhibitory activities on pancreatic lipase, cholesterol esterase, and cholesterol micellization of nipa palm vinegar (NPV).
Total phenolic content was assessed and phenolic compounds were determined using the Folin–Ciocalteu assay and liquid chromatography-mass spectrometry (LC-MS), respectively.
Pancreatic lipase and cholesterol esterase inhibitory activities of the NPV were measured using enzymatic colorimetric assays.
The formation of cholesterol micelles was assessed using a cholesterol assay kit.
The phenolic content of NPV was 167.10 ± 10.15 µg GAE/mL, and LC-MS analyses indicated the presence of gallic acid, isoquercetin, quercetin, catechin, and rutin as bioactive compounds.
Additionally, the NPV inhibited pancreatic lipase and cholesterol esterase activities in a concentration-dependent manner.
Moreover, the NPV also suppressed the formation of cholesterol micellization.
These results suggest that phenolic compounds, especially gallic acid, isoquercetin, quercetin, catechin, and rutin, from NPV may be the main active compounds with possible cholesterol-lowering effects through inhibition of pancreatic lipase and cholesterol esterase activities as well as the inhibition of solubility of cholesterol micelles.
Therefore, NPV may delay postprandial dyslipidemia, and it could be used as a natural source of bioactive compounds with antilipidemic activity.
However, NPV should be extensively evaluated by animal and clinical human studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chatatikun, Moragot& Kwanhian, Wiyada. 2020. Phenolic Profile of Nipa Palm Vinegar and Evaluation of Its Antilipidemic Activities. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1157095
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chatatikun, Moragot& Kwanhian, Wiyada. Phenolic Profile of Nipa Palm Vinegar and Evaluation of Its Antilipidemic Activities. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1157095
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chatatikun, Moragot& Kwanhian, Wiyada. Phenolic Profile of Nipa Palm Vinegar and Evaluation of Its Antilipidemic Activities. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1157095
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1157095
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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