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Effect of Active Ingredients of Chinese Herbal Medicine on the Rejuvenation of Healthy Aging: Focus on Stem Cells
المؤلفون المشاركون
Xu, Jinwen
Wang, Chen
Ling, Shuang
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-18، 18ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-08
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الملخص EN
Stem cells (SCs) are special types of cells with the ability of self-renewal and multidirectional differentiation.
As the organism ages, the ability to maintain homeostasis and regeneration deteriorates and the number and activity of stem cells decline.
Theoretically, the restoration of stem cells might reverse aging.
However, due to their own aging, donor-derived immune rejection, and difficulties in stem cell differentiation control, a series of problems need to be solved to realize the potential for clinical application of stem cells.
Chinese herbal medicine is a nature drug library which is suitable for the long-term treatment of aging-related diseases.
Modern pharmacological studies have revealed that many active ingredients of Chinese herbal medicines with the effect of promoting stem cells growth and differentiation mainly belong to “reinforcing herbs.” In recent years, exploration of natural active ingredients from Chinese herbal medicines for delaying aging, improving the stem cell microenvironment, and promoting the proliferation and differentiation of endogenous stem cells has attracted substantial attention.
This article will focus on active ingredients from Chinese herbs-mediated differentiation of stem cells into particular cell type, like neural cells, endothelial cells, cardiomyocytes, and osteoblasts.
We will also discuss the effects of these small molecules on Wnt, Sonic Hedgehog, Notch, eNOS-cGMP, and MAP kinase signal transduction pathways, as well as reveal the role of estrogen receptor α and PPAR γ on selectively promoting or inhibiting stem cells differentiation.
This review will provide new insights into the health aging strategies of active ingredients in Chinese herbal medicine in regenerative medicine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Chen& Ling, Shuang& Xu, Jinwen. 2020. Effect of Active Ingredients of Chinese Herbal Medicine on the Rejuvenation of Healthy Aging: Focus on Stem Cells. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1157216
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Chen…[et al.]. Effect of Active Ingredients of Chinese Herbal Medicine on the Rejuvenation of Healthy Aging: Focus on Stem Cells. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-18.
https://search.emarefa.net/detail/BIM-1157216
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Chen& Ling, Shuang& Xu, Jinwen. Effect of Active Ingredients of Chinese Herbal Medicine on the Rejuvenation of Healthy Aging: Focus on Stem Cells. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-18.
https://search.emarefa.net/detail/BIM-1157216
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1157216
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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