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The Impact of Natural Product Dietary Supplements on Patients with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
المؤلفون المشاركون
Yang, Juan
Xiong, Donglin
Chon, Tony Y.
Li, Guangxi
Bauer, Brent A.
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-25
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Natural product dietary supplements (NPDS) are frequently used for the treatment of gout, but reliable efficacy and safety data are generally lacking or not well organized to guide clinical decision making.
This review aims to explore the impacts of NPDS for patients with gout.
An electronic literature search was conducted to retrieve data published in English language from databases from inception to August 14, 2019.
Randomized controlled trials (RCTs) that compared NPDS with or without placebo, diet modification, conventional pharmaceutics, or the other Chinese medicine treatment for gout patients were included.
Two authors screened the articles, extracted the data, and assessed the risk of bias of each included trial independently.
Meta-analysis was performed using Review Manager version 5.3.5.
Results.
Nine RCTS were enrolled in this review.
The methodological quality of the nine RCTs was poor.
The study results showed that in the majority of trials, NPDS demonstrated some degree of therapeutic efficacy for joint swelling, pain, and activity limitation.
In contradistinction, serum uric acid (SUA) level (SMD −1.80, 95% CI: −4.45 to 0.86) (p>0.05) and CRP levels (N = 232; SMD, −0.26; 95% CI, −0.55 to 0.04) (p>0.05) did not improve significantly.
The incidence of adverse events (AEs) was not lower in the participants treated with NPDS (N = 750; RR, 0.47; 95% CI, 0.20–1.11) (p>0.05).
Conclusion.
Current existing evidence is not sufficient to provide clinical guidance regarding the efficacy and safety of NPDS as a treatment for gout due to poor trial quality and lack of standardized evaluation criteria.
Larger and more rigorously designed RCTs are needed in the future.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yang, Juan& Li, Guangxi& Xiong, Donglin& Chon, Tony Y.& Bauer, Brent A.. 2020. The Impact of Natural Product Dietary Supplements on Patients with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1157379
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yang, Juan…[et al.]. The Impact of Natural Product Dietary Supplements on Patients with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1157379
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yang, Juan& Li, Guangxi& Xiong, Donglin& Chon, Tony Y.& Bauer, Brent A.. The Impact of Natural Product Dietary Supplements on Patients with Gout: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1157379
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1157379
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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