![](/images/graphics-bg.png)
Effects of Kamishoyosan, a Traditional Japanese Medicine, on Menopausal Symptoms: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial
المؤلفون المشاركون
Takamatsu, Kiyoshi
Ogawa, Mariko
Higuchi, Tsuyoshi
Hayashi, Kunihiko
Mizunuma, Hideki
Takeda, Takashi
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-11
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
Kampo medicine, a traditional Japanese medicine, is widely used in Japan, especially in the field of menopause medicine.
However, few studies have shown evidence-based effects.
This study aimed to confirm the effects of kamishoyosan on menopausal symptoms with a randomized, placebo-controlled, double-blind clinical trial.
Methods.
Subjects were randomly allocated to groups that received either kamishoyosan (n = 101) or a placebo resembling kamishoyosan (n = 104).
The primary outcomes were the change in the number of hot flashes, depression scores, improvements of anxiety, quality of life (QOL), and menopausal symptoms before and 4 and 8 weeks after initiation of treatment with the study drug.
The secondary outcome was drug safety.
Results.
After 8 weeks, the number of hot flashes decreased after treatment in both groups, but there was no significant difference between the two groups.
The changes in SDS scores showed the same results.
Moreover, no significant differences were observed between the two groups in assessments with the STAI, SF-36, and JSOG menopausal index.
No serious adverse effect was reported.
Conclusions.
This first placebo-controlled double-blind randomized trial with kamishoyosan demonstrated that it was safe and had some effects on climacteric symptoms, but not significant compared with placebo.
Some problems, such as placebo effects, in the study of Kampo therapy for menopausal symptoms, were revealed.
This trial is registered with the trial registration number.
UMIN 000006042.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Takamatsu, Kiyoshi& Ogawa, Mariko& Higuchi, Tsuyoshi& Takeda, Takashi& Hayashi, Kunihiko& Mizunuma, Hideki. 2020. Effects of Kamishoyosan, a Traditional Japanese Medicine, on Menopausal Symptoms: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial. Evidence-Based Complementary and Alternative Medicine،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1158449
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Takamatsu, Kiyoshi…[et al.]. Effects of Kamishoyosan, a Traditional Japanese Medicine, on Menopausal Symptoms: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial. Evidence-Based Complementary and Alternative Medicine No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1158449
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Takamatsu, Kiyoshi& Ogawa, Mariko& Higuchi, Tsuyoshi& Takeda, Takashi& Hayashi, Kunihiko& Mizunuma, Hideki. Effects of Kamishoyosan, a Traditional Japanese Medicine, on Menopausal Symptoms: A Randomized, Placebo-Controlled, Double-Blind Clinical Trial. Evidence-Based Complementary and Alternative Medicine. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1158449
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1158449
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)