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Comparison of Dopamine and Norepinephrine Use for the Treatment of Hypotension in Out-Of-Hospital Cardiac Arrest Patients with Return of Spontaneous Circulation
المؤلفون المشاركون
Chen, Chien-Chih
Li, Chao-Jui
Wu, Kuan-Han
Chuang, Po-Chun
Law, Yat-Yin
Chen, Yi-Chuan
المصدر
Emergency Medicine International
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-18
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
In patients experiencing out-of-hospital cardiac arrest (OHCA), hypotension is common after return of spontaneous circulation (ROSC).
Both dopamine and norepinephrine are recommended as inotropic therapeutic agents.
This study aimed to determine the impact of the use of these two medications on hypotension.
This is a multicenter retrospective cohort study.
OHCA patients with ROSC were divided into three groups according to the post resuscitation inotropic agent used for treatment in the emergency department, namely, dopamine, norepinephrine, and dopamine and norepinephrine combined therapy.
Thirty-day survival and favorable neurologic performance were analyzed among the three study groups.
The 30-day survival and favorable neurologic performance rates in the three study groups were 12.5%, 13.0%, and 6.8% as well as 4.9%, 4.3%, and 1.2%, respectively.
On controlling the potential confounding factors by logistic regression, there was no difference between dopamine and norepinephrine treatment in survival and neurologic performance (adjusted odds ratio (aOR): 1.0, 95% confidence interval (CI) 0.48–2.06; aOR: 0.8, 95% CI: 0.28–2.53).
The dopamine and norepinephrine combined treatment group had worse outcome (aOR: 0.6, 95% CI: 0.35–1.18; aOR: 0.2, 95% CI: 0.05–0.89).
In conclusion, there was no significant difference in post-ROSC hypotension treatment between dopamine and norepinephrine in 30-day survival and favorable neurologic performance rates.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Chao-Jui& Wu, Kuan-Han& Chen, Chien-Chih& Law, Yat-Yin& Chuang, Po-Chun& Chen, Yi-Chuan. 2020. Comparison of Dopamine and Norepinephrine Use for the Treatment of Hypotension in Out-Of-Hospital Cardiac Arrest Patients with Return of Spontaneous Circulation. Emergency Medicine International،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1159132
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Chao-Jui…[et al.]. Comparison of Dopamine and Norepinephrine Use for the Treatment of Hypotension in Out-Of-Hospital Cardiac Arrest Patients with Return of Spontaneous Circulation. Emergency Medicine International No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1159132
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Chao-Jui& Wu, Kuan-Han& Chen, Chien-Chih& Law, Yat-Yin& Chuang, Po-Chun& Chen, Yi-Chuan. Comparison of Dopamine and Norepinephrine Use for the Treatment of Hypotension in Out-Of-Hospital Cardiac Arrest Patients with Return of Spontaneous Circulation. Emergency Medicine International. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1159132
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159132
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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