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Significance of Preoperative Systemic Immune Score for Stage I Gastric Cancer Patients
المؤلفون المشاركون
Lu, Jun
Li, Ping
Wang, Jia-Bin
Xie, Jian-wei
Chen, Qi-yue
Cao, Long-long
Lin, Mi
Tu, Ru-Hong
Lin, Jian-xian
Zheng, Chao-Hui
Huang, Chang-Ming
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
Determining preferences regarding the benefits of adjuvant chemotherapy (AC) for stage I GC is critical.
Methods.
We retrospectively reviewed 1069 patients with pathologically confirmed stage I GC who underwent R0 gastrectomy between 2006 and 2014.
Univariate and multivariate survival analyses were conducted.
Systemic inflammation factors were used to develop a scoring system for predicting AC benefits.
Results.
With a median follow-up of 47 months (range 3–113 months), the 5-year overall survival (OS) rate was 90.5%.
The patient score was 1 for either a pretreatment hypoalbuminemia or elevated derived neutrophil-lymphocyte ratio (dNLR) and was 0 otherwise.
The SIS served as an independent prognostic factor for reduced OS.
AC was delivered to 13.5% (144/1069) of all patients.
Compared to surgery alone, AC had no significant effect on survival in both the entire cohort and the IA/IB subgroup.
However, in the high-risk group (SIS = 2), patients with AC had a significantly better OS than those undergoing surgery alone.
Conclusions.
Patients with SIS = 2 may benefit from AC and thus may be considered candidates for adjuvant treatment.
However, to confirm our findings, future prospective studies are warranted.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lu, Jun& Cao, Long-long& Li, Ping& Xie, Jian-wei& Wang, Jia-Bin& Lin, Jian-xian…[et al.]. 2018. Significance of Preoperative Systemic Immune Score for Stage I Gastric Cancer Patients. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1159517
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lu, Jun…[et al.]. Significance of Preoperative Systemic Immune Score for Stage I Gastric Cancer Patients. Gastroenterology Research and Practice No. 2018 (2018), pp.1-10.
https://search.emarefa.net/detail/BIM-1159517
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lu, Jun& Cao, Long-long& Li, Ping& Xie, Jian-wei& Wang, Jia-Bin& Lin, Jian-xian…[et al.]. Significance of Preoperative Systemic Immune Score for Stage I Gastric Cancer Patients. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-10.
https://search.emarefa.net/detail/BIM-1159517
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159517
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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