Hypertriglyceridemia and Its Association with HbA1c Test: A Prospective In Vivo Controlled Study
المؤلفون المشاركون
Mancillas-Adame, Leonardo G.
González-González, José Gerardo
Rodríguez-Gutiérrez, René
Rodríguez-Tamez, Giselle
Diaz Gonzalez-Colmenero, Alejandro
Solis-Pacheco, Ricardo Cesar
Elizondo-Plazas, Ana Sofia
Santos-Santillana, Karla M.
Gonzalez-Sariñana, Linda
Gonzalez-Nava, Victoria
المصدر
International Journal of Endocrinology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-12
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Hypertriglyceridemia and hyperglycemia coexist in 30-60% of patients with diabetes.
The impact of hypertriglyceridemia regarding HbA1c assay reliability remains uncertain.
Therefore, we conducted a prospective in vivo controlled study with the aim of defining the association between triglyceride levels and HbA1c.
Methods.
A total of 44 patients with an index-hospital admission diagnosis of diabetic ketoacidosis or hypertriglyceridemia-induced pancreatitis, as a model for acute elevation of triglycerides, were recruited.
Blood samples were drawn for the measurement of HbA1c, triglycerides, glucose, and hemoglobin at baseline and subsequently 24 and 48 hours after admission.
HbA1c analysis was performed with high-performance liquid chromatography Bio-Rad D10 (NGSP approved).
Results.
All patients completed the study protocol.
A difference between mean triglycerides from day 0 (baseline) to day 2 of 1567.2 mg/dL was observed.
We found a difference between mean serum HbA1c from days 0 to 2 of 0.09% [1 mmol/mol] (p=0.004).
Moreover, a weak correlation between the mean difference of HbA1c and triglycerides from baseline to day 2 was found to be statistically significant (r=0.256, p=0.015).
None of these findings, however, are clinically significant.
Conclusion.
Triglycerides do not impair the interpretation of HbA1c assay.
Patients and clinicians can now be confident that hypertriglyceridemia is not an important factor when interpreting HbA1c results.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Rodríguez-Gutiérrez, René& Mancillas-Adame, Leonardo G.& Rodríguez-Tamez, Giselle& Diaz Gonzalez-Colmenero, Alejandro& Solis-Pacheco, Ricardo Cesar& Elizondo-Plazas, Ana Sofia…[et al.]. 2019. Hypertriglyceridemia and Its Association with HbA1c Test: A Prospective In Vivo Controlled Study. International Journal of Endocrinology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1159555
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Rodríguez-Gutiérrez, René…[et al.]. Hypertriglyceridemia and Its Association with HbA1c Test: A Prospective In Vivo Controlled Study. International Journal of Endocrinology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1159555
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Rodríguez-Gutiérrez, René& Mancillas-Adame, Leonardo G.& Rodríguez-Tamez, Giselle& Diaz Gonzalez-Colmenero, Alejandro& Solis-Pacheco, Ricardo Cesar& Elizondo-Plazas, Ana Sofia…[et al.]. Hypertriglyceridemia and Its Association with HbA1c Test: A Prospective In Vivo Controlled Study. International Journal of Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1159555
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1159555
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر