The Cerebellum Posterior Lobe Associates with the Exophthalmos of Primary Hyperthyroidism: A Resting-State fMRI Study
المؤلفون المشاركون
Liu, Wen-Feng
Shu, Yong-Qiang
Zhu, Pei-Wen
Li, Biao
Shi, Wen-Qing
Lin, Qi
Liu, Yu-Xin
Zhang, Meng-Yao
Min, You-Lan
Yuan, Qing
Shao, Yi
المصدر
International Journal of Endocrinology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Exophthalmos occurs in patients with primary hyperthyroidism.
There were few studies about the changes of brain functional networks of patients with exophthalmos of primary hyperthyroidism (EOPH).
However, differences in spontaneous brain activity in patients with EOPH remain unclear.
Objective.
This study explored alterations in the brain functional networks of patients with EOPH using a voxel-wise degree centrality (DC) method.
Methods.
A total of 20 patients with EOPH (8 men and 12 women) were enrolled.
In addition, 20 patients with primary hyperthyroidism without exophthalmos, matched in age, sex, and education status, were enrolled as a control group.
The Hospital Anxiety and Depression Scale was used to assess the anxiety and depression status of participants.
All participants were examined using resting-state functional MRI.
Changes in spontaneous brain activity were investigated using the DC method.
To distinguish between the DC values of the patients with EOPH and those of the control group, we analyzed the receiver operating characteristic (ROC) curve.
The interrelationships between the DC values and clinical variables in the patients with EOPH were evaluated using Pearson’s correlation coefficient.
Results.
Patients with EOPH exhibited notably lower DC values in the cerebellum posterior lobe than the control group.
In addition, there were negative correlations between the anxiety scores (AS) and the depression scores (DS) and DC values of the cerebellum posterior lobe.
The ROC curve analysis of the cerebellum posterior lobe demonstrated that the area under the curve method had a high diagnostic accuracy.
Conclusions.
Our study was the first, to our knowledge, to explore changes in the brains of patients with EOPH using the DC method.
The DC value was significantly different in the cerebellum posterior lobe in patients with EOPH, indicating that the cerebellum posterior lobe is associated with EOPH.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liu, Wen-Feng& Shu, Yong-Qiang& Zhu, Pei-Wen& Li, Biao& Shi, Wen-Qing& Lin, Qi…[et al.]. 2019. The Cerebellum Posterior Lobe Associates with the Exophthalmos of Primary Hyperthyroidism: A Resting-State fMRI Study. International Journal of Endocrinology،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1160069
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liu, Wen-Feng…[et al.]. The Cerebellum Posterior Lobe Associates with the Exophthalmos of Primary Hyperthyroidism: A Resting-State fMRI Study. International Journal of Endocrinology No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1160069
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liu, Wen-Feng& Shu, Yong-Qiang& Zhu, Pei-Wen& Li, Biao& Shi, Wen-Qing& Lin, Qi…[et al.]. The Cerebellum Posterior Lobe Associates with the Exophthalmos of Primary Hyperthyroidism: A Resting-State fMRI Study. International Journal of Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1160069
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1160069
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر