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Tissue-Engineered Vascular Graft of Small Diameter Based on Electrospun Polylactide Microfibers
المؤلفون المشاركون
Popryadukhin, P. V.
Popov, G. I.
Yukina, G. Yu.
Dobrovolskaya, I. P.
Ivan’kova, E. M.
Vavilov, V. N.
Yudin, V. E.
المصدر
International Journal of Biomaterials
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-08
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Tubular vascular grafts 1.1 mm in diameter based on poly(L-lactide) microfibers were obtained by electrospinning.
X-ray diffraction and scanning electron microscopy data demonstrated that the samples treated at T=70°C for 1 h in the fixed state on a cylindrical mandrel possessed dense fibrous structure; their degree of crystallinity was approximately 44%.
Strength and deformation stability of these samples were higher than those of the native blood vessels; thus, it was possible to use them in tissue engineering as bioresorbable vascular grafts.
The experiments on including implantation into rat abdominal aorta demonstrated that the obtained vascular grafts did not cause pathological reactions in the rats; in four weeks, inner side of the grafts became completely covered with endothelial cells, and fibroblasts grew throughout the wall.
After exposure for 12 weeks, resorption of PLLA fibers started, and this process was completed in 64 weeks.
Resorbed synthetic fibers were replaced by collagen and fibroblasts.
At that time, the blood vessel was formed; its neointima and neoadventitia were close to those of the native vessel in structure and composition.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Popryadukhin, P. V.& Popov, G. I.& Yukina, G. Yu.& Dobrovolskaya, I. P.& Ivan’kova, E. M.& Vavilov, V. N.…[et al.]. 2017. Tissue-Engineered Vascular Graft of Small Diameter Based on Electrospun Polylactide Microfibers. International Journal of Biomaterials،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1160096
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Popryadukhin, P. V.…[et al.]. Tissue-Engineered Vascular Graft of Small Diameter Based on Electrospun Polylactide Microfibers. International Journal of Biomaterials No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1160096
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Popryadukhin, P. V.& Popov, G. I.& Yukina, G. Yu.& Dobrovolskaya, I. P.& Ivan’kova, E. M.& Vavilov, V. N.…[et al.]. Tissue-Engineered Vascular Graft of Small Diameter Based on Electrospun Polylactide Microfibers. International Journal of Biomaterials. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1160096
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1160096
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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