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Benign Adrenocortical Tumors and the Detection of Nonadrenal Neoplasia
المؤلفون المشاركون
Hao, Meng
Luque-Fernandez, Miguel Angel
Lopez, Diana
Cote, Kathryn
Newfield, Jessica
Connors, Molly
Vaidya, Anand
المصدر
International Journal of Endocrinology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-11-03
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Context.
Patients with adrenocortical tumors have been frequently observed to have nonadrenal neoplasia.
Objective.
To investigate whether patients with benign adrenocortical tumors have a higher likelihood of having nonadrenal neoplasia detected.
Design and Participants.
Case-control study of patients with benign adrenocortical tumors (cases; n = 400) and normal adrenal glands (controls; n = 400), who underwent repeated abdominal cross-sectional imaging.
Main Outcomes.
Primary analyses: association between case-control status and benign abdominal neoplasia detected via cross-sectional imaging.
Secondary analyses: association between case-control status and tumors detected via other imaging modalities.
Results.
The mean interval of abdominal imaging was 4.7 (SD = 3.8) years for cases and 5.9 (4.8) years for controls.
Cases were more likely to have detected intraductal papillary mucinous neoplasms (IPMNs) of the pancreas (8.5% vs.
4.5%, adjusted OR = 2.22, 95% CI (1.11, 4.63)) compared with controls.
In secondary analyses, cases were more likely to have detected thyroid nodules (25.5% vs.
17.0%, adjusted OR = 1.77, 95% CI (1.15, 2.74)), hyperparathyroidism or parathyroid adenomas (3.5% vs.
1.3%, adjusted OR = 3.00, 95% CI (1.00, 11.64)), benign breast masses (6.0% vs.
3.3%, adjusted OR = 3.25, 95% CI (1.28, 8.78)), and benign prostatic hyperplasia (20.5% vs.
5.3%, adjusted OR = 3.20, 95% CI (1.14, 10.60)).
Using a composite outcome, cases had higher odds of detection of the composite of IPMN, thyroid nodules, parathyroid tumors, benign breast masses, and prostate hyperplasia (adjusted OR = 2.36, 95% CI: 1.60, 3.50) when compared with controls.
Conclusions.
Patients with benign adrenocortical tumors had higher odds of detected pancreatic IPMN, as well as thyroid nodules, parathyroid tumors, benign breast masses, and prostate hyperplasia compared with patients with normal adrenal glands.
These associations may have important implications for patient care and healthcare economics, regardless of whether they reflect incidental discoveries due to imaging detection or frequency bias, or a common risk for developing multiple neoplasia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hao, Meng& Luque-Fernandez, Miguel Angel& Lopez, Diana& Cote, Kathryn& Newfield, Jessica& Connors, Molly…[et al.]. 2019. Benign Adrenocortical Tumors and the Detection of Nonadrenal Neoplasia. International Journal of Endocrinology،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1165081
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hao, Meng…[et al.]. Benign Adrenocortical Tumors and the Detection of Nonadrenal Neoplasia. International Journal of Endocrinology No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1165081
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hao, Meng& Luque-Fernandez, Miguel Angel& Lopez, Diana& Cote, Kathryn& Newfield, Jessica& Connors, Molly…[et al.]. Benign Adrenocortical Tumors and the Detection of Nonadrenal Neoplasia. International Journal of Endocrinology. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1165081
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1165081
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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