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The Therapeutic Effect of a Multistrain Probiotic on Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study
المؤلفون المشاركون
Lee, Seok-Hoon
Joo, Nam-Seok
Kim, Kwang-Min
Kim, Kyu-Nam
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-06
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Backgrounds.
Recent studies suggest that diarrhea-predominant irritable bowel syndrome (IBS) is associated with intestinal bacterial microflora, colonic inflammation, and small intestinal bacterial overgrowth (SIBO).
The purpose of this study was to evaluate the effect of a multistrain probiotic intake on these associated factors in patients with diarrhea-predominant IBS.
Methods.
The recruited volunteers were adults who were diagnosed with diarrhea-predominant IBS according to the Rome III criteria.
After 8 weeks of probiotic ingestion, changes in gastrointestinal symptoms, fecal microbiome, SIBO, and fecal calprotectin were determined.
Results.
There was an increase in beneficial bacteria (41.2 ± 16.8% vs.
53.7 ± 15.3%, P=0.018) and a decrease in harmful bacteria (13.0 ± 13.9% vs.
4.7 ± 4.0%, P=0.010) in the microbial stool analysis.
The SIBO prevalence also decreased at the end of treatment.
However, the average levels of fecal calprotectin showed a decreasing tendency, without reaching statistical significance (364.4 ± 729.1 mg/kg vs.
200.9 ± 347.6 mg/kg, P=0.375).
Conclusion.
Treatment with a multistrain probiotic for 8 weeks led to significant increases in beneficial bacteria in the gut as well as the improvement of gastrointestinal symptoms.
This study is registered at the Clinical Research Information Service (KCT0002906).
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lee, Seok-Hoon& Joo, Nam-Seok& Kim, Kwang-Min& Kim, Kyu-Nam. 2018. The Therapeutic Effect of a Multistrain Probiotic on Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1165768
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lee, Seok-Hoon…[et al.]. The Therapeutic Effect of a Multistrain Probiotic on Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study. Gastroenterology Research and Practice No. 2018 (2018), pp.1-8.
https://search.emarefa.net/detail/BIM-1165768
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lee, Seok-Hoon& Joo, Nam-Seok& Kim, Kwang-Min& Kim, Kyu-Nam. The Therapeutic Effect of a Multistrain Probiotic on Diarrhea-Predominant Irritable Bowel Syndrome: A Pilot Study. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-8.
https://search.emarefa.net/detail/BIM-1165768
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1165768
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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