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Prognostic Roles of Inflammatory Markers in Pancreatic Cancer: Comparison between the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio
المؤلفون المشاركون
Oh, Dongwook
Pyo, Jung-Soo
Son, Byoung Kwan
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-07
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background/Objectives.
This meta-analysis is aimed at investigating the prognostic roles of the inflammatory markers neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) in patients with pancreatic cancer.
Methods.
The correlations between high inflammatory marker expression levels and prognosis in 7105 patients with pancreatic cancer from 34 eligible studies were investigated.
Additionally, subgroup analyses based on study location, tumor stage, treatment, and value cutoffs were performed.
Results.
High NLR and PLR values were considered to be 2.0–5.0 and 150–200, respectively.
Using a random-effects model, the estimated rates of high NLR and PLR were 0.379 (95% confidence interval [CI] 0.310–0.454) and 0.490 (95% CI 0.438–0.543), respectively.
High NLRs were frequently found in patients with lower tumor stages and in those who underwent surgery.
There were significant correlations between high NLR and PLR and poor survival rates (hazard ratio [HR] 1.737, 95% CI 1.502–2.009 and HR 1.143, 95% CI 1.037–1.259, resp.).
Interestingly, the NLR and PLR had no prognostic value in patients who underwent chemoradiotherapy.
Conclusion.
Taken together, our results showed that inflammatory markers are useful for predicting prognosis in patients with pancreatic cancer.
The NLR is a more suitable parameter for predicting prognosis regardless of the patient’s condition.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oh, Dongwook& Pyo, Jung-Soo& Son, Byoung Kwan. 2018. Prognostic Roles of Inflammatory Markers in Pancreatic Cancer: Comparison between the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio. Gastroenterology Research and Practice،Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1165990
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oh, Dongwook…[et al.]. Prognostic Roles of Inflammatory Markers in Pancreatic Cancer: Comparison between the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio. Gastroenterology Research and Practice No. 2018 (2018), pp.1-9.
https://search.emarefa.net/detail/BIM-1165990
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oh, Dongwook& Pyo, Jung-Soo& Son, Byoung Kwan. Prognostic Roles of Inflammatory Markers in Pancreatic Cancer: Comparison between the Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio. Gastroenterology Research and Practice. 2018. Vol. 2018, no. 2018, pp.1-9.
https://search.emarefa.net/detail/BIM-1165990
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1165990
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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