Molecular Antimicrobial Resistance of Neisseria gonorrhoeae in a Moroccan Area
المؤلفون المشاركون
Karim, Safae
Bouchikhi, Chahrazed
Banani, Abdelaziz
El Fatemi, Hinde
Souho, Tiatou
Erraghay, Sanaa
Bennani, Bahia
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-21
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Objectives.
To identify the prevalence and the types of Neisseria gonorrhoeae (NG) resistance plasmids-mediated penicillin (PPNG) and tetracycline (TRNG), the ciprofloxacin resistance (CRNG), and related risk factors of each types of resistance.
Methods.
The beta-lactamase-producing plasmid types (Africa, Asia, and Toronto), tetM tetracycline resistance plasmid types (America and Dutch), and the determination of the Ser-91 mutation of GyrA were detected by specifics PCRs on 149 diagnosed NG positives samples followed by Hinf1 digestion for tetM and gyrA mutation.
Results.
135 (90.1%) samples showed a profile of molecular resistance to at least one antibiotic with predominance of ciprofloxacin resistance.
In fact, 36 (24.2%) and 69 (46.3%) cases harbored PPNG and TRNG, respectively, and 116 (77.9%) cases showed the mutation Ser-91 of GyrA (CRNG).
From a total of 36 PPNG isolates, the Toronto, Asian, and Toronto/Asian types were detected in 13 (36.1%), 10 (27.8%), and 13 (36.1%) cases, respectively, whereas the African type was not detected.
In addition, the American type of TRNG was detected in 92.8% (64/69) of cases, while the Dutch type was detected in 7.2% (5/69) of cases.
The association of demographics and clinical variables with NG resistance to ciprofloxacin, penicillin, and tetracycline was studied and the risk factors have been determined.
Conclusion.
Resistance to penicillin, tetracycline, and ciprofloxacin among NG samples positives remained at high levels in Morocco as determined by molecular profile.
So, the use of molecular tools for NG antimicrobial resistance detection can help in the management and spread limitation of this infection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Karim, Safae& Bouchikhi, Chahrazed& Banani, Abdelaziz& El Fatemi, Hinde& Souho, Tiatou& Erraghay, Sanaa…[et al.]. 2018. Molecular Antimicrobial Resistance of Neisseria gonorrhoeae in a Moroccan Area. Infectious Diseases in Obstetrics and Gynecology،Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1166094
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Karim, Safae…[et al.]. Molecular Antimicrobial Resistance of Neisseria gonorrhoeae in a Moroccan Area. Infectious Diseases in Obstetrics and Gynecology No. 2018 (2018), pp.1-11.
https://search.emarefa.net/detail/BIM-1166094
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Karim, Safae& Bouchikhi, Chahrazed& Banani, Abdelaziz& El Fatemi, Hinde& Souho, Tiatou& Erraghay, Sanaa…[et al.]. Molecular Antimicrobial Resistance of Neisseria gonorrhoeae in a Moroccan Area. Infectious Diseases in Obstetrics and Gynecology. 2018. Vol. 2018, no. 2018, pp.1-11.
https://search.emarefa.net/detail/BIM-1166094
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166094
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر