Encapsulation of Bifidobacterium pseudocatenulatum Strain G4 within Bovine Gelatin-Genipin-Sodium Alginate Combinations: Optimisation Approach Using Face Central Composition Design-Response Surface Methodology (FCCD-RSM)‎

المؤلفون المشاركون

Mustafa, Shuhaimi
ABD Manap, Mohd Yazid
Ahmad, Siti Aqlima
Mohammad, Rosfarizan
Dahalan, Farrah Aini
Ariff, Arbakariya Bin
Abdul Khalil, Khalilah

المصدر

International Journal of Microbiology

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-04-10

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الطب البشري

الملخص EN

Bovine gelatin is a biopolymer which has good potential to be used in encapsulating matrices for probiotic candidate Bifidobacterium pseudocatenulatum strain G4 (G4) because of its amphoteric nature characteristic.

Beads were prepared by the extrusion method using genipin and sodium alginate as a cross-linking agent.

The optimisation of bovine gelatin-genipin-sodium alginate combinations was carried out using face central composition design (FCCD) to investigate G4 beads’ strength, before and after exposed to simulated gastric (SGF), intestinal fluids (SIF), and encapsulation yield.

A result of ANOVA and the polynomial regression model revealed the combinations of all three factors have a significant effect (p<0.05) on the bead strength.

Meanwhile, for G4 encapsulation yield, only genipin showed less significant effect on the response.

However, the use of this matrix remained due to the intermolecular cross-linking ability with bovine gelatin.

Optimum compositions of bovine gelatin-genipin-sodium alginate were obtained at 11.21% (w/v), 1.96 mM, and 2.60% (w/v), respectively.

A model was validated for accurate prediction of the response and showed no significant difference (p>0.05) with experimental values.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Abdul Khalil, Khalilah& Mustafa, Shuhaimi& Mohammad, Rosfarizan& Ariff, Arbakariya Bin& Ahmad, Siti Aqlima& Dahalan, Farrah Aini…[et al.]. 2019. Encapsulation of Bifidobacterium pseudocatenulatum Strain G4 within Bovine Gelatin-Genipin-Sodium Alginate Combinations: Optimisation Approach Using Face Central Composition Design-Response Surface Methodology (FCCD-RSM). International Journal of Microbiology،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1166211

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Abdul Khalil, Khalilah…[et al.]. Encapsulation of Bifidobacterium pseudocatenulatum Strain G4 within Bovine Gelatin-Genipin-Sodium Alginate Combinations: Optimisation Approach Using Face Central Composition Design-Response Surface Methodology (FCCD-RSM). International Journal of Microbiology No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1166211

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Abdul Khalil, Khalilah& Mustafa, Shuhaimi& Mohammad, Rosfarizan& Ariff, Arbakariya Bin& Ahmad, Siti Aqlima& Dahalan, Farrah Aini…[et al.]. Encapsulation of Bifidobacterium pseudocatenulatum Strain G4 within Bovine Gelatin-Genipin-Sodium Alginate Combinations: Optimisation Approach Using Face Central Composition Design-Response Surface Methodology (FCCD-RSM). International Journal of Microbiology. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1166211

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1166211