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Analysis of Bacterial and Fungal Infections after Cytoreduction Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Observational Single-Centre Study
المؤلفون المشاركون
Albukhari, Talat A. M.
Nafady-Hego, Hanaa
Elgendy, Hamed
Abd Elmoneim, Hanan M.
Nafady, Asmaa
Alzahrani, Abdulaziz M.
المصدر
International Journal of Microbiology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-08-01
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Introduction.
While hyperthermic intraperitoneal chemotherapy (HIPEC) after cytoreduction surgery (CRS) has been shown to improve patient survival and disease-free progression in peritoneal carcinoma (PC) patients, the procedure relates to a high postoperative infection rate.
Herein, we report the bacterial and fungal infections after CRS and HIPEC from a single institution in Saudi Arabia.
Patients and Methods.
A prospective observational study was conducted on 38 patients with PC selected for CRS/HIPEC procedure between 2012 and 2015 in our centre.
Results.
Postoperative bacterial and fungal infection within 100 days was 42.2%, bacterial infection was reported always, and fungal infection was reported in 5 (13.2%) cases.
Infections from the surgical site were considered the most common infection site.
Multidrug-resistant extended-spectrum beta-lactamase (ESBL) Escherichia coli was the most frequent isolate, followed by multidrug-resistant Acinetobacter baumannii and Pseudomonas aeruginosa.
Lower preoperative albumin and a prolonged preoperative activated partial thromboplastin time (APTT) are associated with postoperative infections, while a prolonged preoperative hospital stay (hazard ratio (HR) = 1.064; confidence interval (CI) = 1.002–1.112; P=0.042) and more intraoperative blood loss (>10%) (HR = 3.919; 95% CI = 1.024–14.995; P=0.046) were independent risk factors for postoperative infections.
Three cases died during the follow-up period; all were due to infection.
Discussion.
The infection rate in our centre compared to previous studies of comparable patients was matching.
Effective management of postoperative infections should be considered, and identified risk factors in this study can help to focus on effective prevention and treatment strategies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Albukhari, Talat A. M.& Nafady-Hego, Hanaa& Elgendy, Hamed& Abd Elmoneim, Hanan M.& Nafady, Asmaa& Alzahrani, Abdulaziz M.. 2019. Analysis of Bacterial and Fungal Infections after Cytoreduction Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Observational Single-Centre Study. International Journal of Microbiology،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1166265
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Albukhari, Talat A. M.…[et al.]. Analysis of Bacterial and Fungal Infections after Cytoreduction Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Observational Single-Centre Study. International Journal of Microbiology No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1166265
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Albukhari, Talat A. M.& Nafady-Hego, Hanaa& Elgendy, Hamed& Abd Elmoneim, Hanan M.& Nafady, Asmaa& Alzahrani, Abdulaziz M.. Analysis of Bacterial and Fungal Infections after Cytoreduction Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Observational Single-Centre Study. International Journal of Microbiology. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1166265
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166265
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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