Serum ZAG Levels Were Associated with eGFR Mild Decrease in T2DM Patients with Diabetic Nephropathy
المؤلفون المشاركون
Huang, Ping
Li, Yan
Wang, Jing
Zheng, Caixia
Qu, Bin
Wang, Ou
Gong, Fengying
Xu, Ling-ling
Yu, Weihong
Niu, Meng
المصدر
International Journal of Endocrinology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-02
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the changes of serum zinc-α2-glycoprotein (ZAG) in type 2 diabetes mellitus (T2DM) with eGFR mild decrease.
Subjects and Methods.
A total of 438 T2DM patients (61.3 ± 4.0 y) were recruited and the demographic, anthropometric, and biochemical parameters were all collected.
Serum ZAG levels were determined by commercially available ELISA kits.
Results.
The proportion of T2DM patients with the high tertile ZAG levels was 11.9% higher in patients with mildly decreased estimated glomerular filtration rate (eGFR) (<90 mL/min/1.73 m2) than those with the low tertile ZAG levels P=0.038.
The probability of the eGFR<90 mL/min/1.73 m2 in patients with the high ZAG levels was 94% higher than those with the low serum ZAG levels after adjusting for age, gender, and education [OR = 1.94, 95% CI (1.17–3.23), P=0.0094].
This phenomenon was more likely to be observed in the condition of uACR ≥ 2.7 mg/mmol, WC ≥ 90 cm for men, or WC ≥ 85 cm for women.
Conclusion.
Serum ZAG levels were firstly found to be related with eGFR in T2DM patients.
The patients with the high tertile ZAG levels were more likely to have mildly eGFR decrease, especially for female patients with higher uACR and bigger WC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Ling-ling& Yu, Weihong& Niu, Meng& Zheng, Caixia& Qu, Bin& Li, Yan…[et al.]. 2017. Serum ZAG Levels Were Associated with eGFR Mild Decrease in T2DM Patients with Diabetic Nephropathy. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1166416
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Ling-ling…[et al.]. Serum ZAG Levels Were Associated with eGFR Mild Decrease in T2DM Patients with Diabetic Nephropathy. International Journal of Endocrinology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1166416
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Ling-ling& Yu, Weihong& Niu, Meng& Zheng, Caixia& Qu, Bin& Li, Yan…[et al.]. Serum ZAG Levels Were Associated with eGFR Mild Decrease in T2DM Patients with Diabetic Nephropathy. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1166416
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166416
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر