The Associations of Serum Uric Acid with Obesity-Related Acanthosis nigricans and Related Metabolic Indices
المؤلفون المشاركون
Sheng, Hui
Cheng, Xiaoyun
Yang, Peng
Bu, Le
Qu, Shen
Zhu, Cuiling
Gao, Mingming
Rampersad, Sharvan
You, Hui
Cui, Ran
Sheng, Chun-Jun
المصدر
International Journal of Endocrinology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-07
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objective.
Recent studies have shown that hyperuricemia (HUA) is associated with hypertension, dyslipidemia, insulin resistance, and metabolic syndrome (MetS).
We aimed to examine the relationship of serum UA with Acanthosis nigricans (AN) and related metabolic indices in obese patients.
Methods.
A cross-sectional study with 411 obese patients recruited from our department was analyzed in this study.
Weight, body mass index (BMI), UA, lipid profile, liver function, and renal function were measured in all participants.
Oral glucose tolerance tests were performed, and serum glucose, insulin, and C peptide were measured at 0, 30, 60, 120, and 180 min.
Results.
AN group had higher serum UA levels than OB group.
Circulating UA levels were associated with BMI, dyslipidemia, hypertension, IR, and AN.
In logistic regression analyses (multivariable‐adjusted), a high serum UA level was associated with high odds ratios (ORs) (95% confidence interval [CI]) for AN in females (ORs = 3.00 and 95% CI [1.02–8.84]) and males (ORs = 6.07 and 95% CI [2.16–17.06]) in the highest quartile (Q4) of serum UA.
Conclusions.
Serum UA levels were positively associated with multiple metabolic abnormalities including obesity, hypertension, hyperglycemia, hyperlipidemia, and AN and may be an important risk factor in the development of AN; further evidences in vitro and in vivo are needed to investigate the direct or indirect relationship.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhu, Cuiling& Cui, Ran& Gao, Mingming& Rampersad, Sharvan& You, Hui& Sheng, Chun-Jun…[et al.]. 2017. The Associations of Serum Uric Acid with Obesity-Related Acanthosis nigricans and Related Metabolic Indices. International Journal of Endocrinology،Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1166420
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhu, Cuiling…[et al.]. The Associations of Serum Uric Acid with Obesity-Related Acanthosis nigricans and Related Metabolic Indices. International Journal of Endocrinology No. 2017 (2017), pp.1-9.
https://search.emarefa.net/detail/BIM-1166420
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhu, Cuiling& Cui, Ran& Gao, Mingming& Rampersad, Sharvan& You, Hui& Sheng, Chun-Jun…[et al.]. The Associations of Serum Uric Acid with Obesity-Related Acanthosis nigricans and Related Metabolic Indices. International Journal of Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-9.
https://search.emarefa.net/detail/BIM-1166420
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166420
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر