High Incidence of Moderately Reduced Renal Function and Lead Bioaccumulation in Agricultural Workers in Assin South District, Ghana: A Community-Based Case-Control Study
المؤلفون المشاركون
Adu, Patrick
Ephraim, Richard K. D.
Forkuo, Eric Kumah
Issah, Abubakari
Asumadu, Isaac Owusu
Cadman-Sackey, Emmanuel
Quarshie, Augustina A. A.
Gyabaa, Sampson
المصدر
International Journal of Nephrology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-30
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
The quest to enhance agricultural productivity and crop yields has led to increased use of agrochemicals on a global scale.
Long-term use of these agrochemicals may be associated with adverse health implications.
Objective.
To assess haematological indices, renal function, heavy metal bioaccumulation in farmers and sprayers, and their use of personal protective equipment (PPE).
Materials and Methods.
This community-based case-control study was conducted from January 2018 to June 2018 in the Assin South District, Central Region, Ghana.
A total of 144 participants were conveniently sampled: 83 agricultural workers (cases) and 61 indigenes with no direct exposure to agrochemicals (controls).
Structured questionnaire was used to obtain demographic data as well as agricultural work practices followed by cases.
Venous blood samples were drawn from participants and used for estimating full blood count and renal function (serum creatinine (CRE), blood-urea nitrogen (BUN), BUN : CRE ratio, and estimated GFR (eGFR)).
Serum lead, arsenic, and cadmium levels were estimated using the Varian AA 240FS atomic spectrometer in an acetylene-air flame.
Results.
The median RBC (4.49 vs.
4.92 × 1012/L), haemoglobin (12.50 vs.
13.70 g/dL), and platelet (220.00 vs.
268.00) counts were significantly lower in cases.
A significantly higher proportion of cases were classified as anaemic or having microcytic cells compared to controls.
Also, serum urea (4.08 vs.
3.41; p=0.0009), creatinine (108.10 vs.
101.10; p=0.0286), and BUN : CRE ratio (19.75 vs.
17.84) were significantly higher in cases.
Additionally, 18.1% of cases were classified as having moderately reduced renal function compared to only 6.6% of controls.
Moreover, a significantly higher proportion of cases had detectable serum lead (55.6% vs.
16.4%) and arsenic (53.1% vs.
9.8%) levels compared to controls.
However, on average, 80% of agricultural workers did not use personal protective equipment (PPE) when applying agrochemicals; 84.3% of used agrochemical containments were discarded near the river/canal.
Conclusion.
Neglect of the use of PPE may be predisposing the agrochemical workers and community to lead and arsenic bioaccumulation with a consequent reduced haematological and renal function.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Adu, Patrick& Forkuo, Eric Kumah& Issah, Abubakari& Asumadu, Isaac Owusu& Cadman-Sackey, Emmanuel& Quarshie, Augustina A. A.…[et al.]. 2019. High Incidence of Moderately Reduced Renal Function and Lead Bioaccumulation in Agricultural Workers in Assin South District, Ghana: A Community-Based Case-Control Study. International Journal of Nephrology،Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1166489
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Adu, Patrick…[et al.]. High Incidence of Moderately Reduced Renal Function and Lead Bioaccumulation in Agricultural Workers in Assin South District, Ghana: A Community-Based Case-Control Study. International Journal of Nephrology No. 2019 (2019), pp.1-7.
https://search.emarefa.net/detail/BIM-1166489
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Adu, Patrick& Forkuo, Eric Kumah& Issah, Abubakari& Asumadu, Isaac Owusu& Cadman-Sackey, Emmanuel& Quarshie, Augustina A. A.…[et al.]. High Incidence of Moderately Reduced Renal Function and Lead Bioaccumulation in Agricultural Workers in Assin South District, Ghana: A Community-Based Case-Control Study. International Journal of Nephrology. 2019. Vol. 2019, no. 2019, pp.1-7.
https://search.emarefa.net/detail/BIM-1166489
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166489
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر