Tumor Size as a Critical Prognostic Factor in T1-2 Stage Esophageal Cancer
المؤلفون المشاركون
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-17
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
Tumor size has been measured in esophageal cancer for decades, but the role of tumor size in relation to T stage in the prediction of survival is still underappreciated.
Thus, the present study is aimed at investigating the influence of T stage on the predictive value of tumor size in clinical stage I–IV esophageal cancer patients.
Materials and Methods.
Data were obtained from the Surveillance, Epidemiology, and End Results Program (SEER) cancer registry program.
Cox proportional hazards regression was utilized to identify the independent prognostic ability of the factor.
Kaplan-Meier analysis was used to estimate the distribution of survival outcome.
Harrell’s concordance index (c-index) was used to quantify the predictive ability of the prognostic model and prognostic factor.
Results.
According to the T stage, subgroup analysis showed that tumor size was not an independent risk factor in T3 and T4 stage esophageal cancer patients.
Furthermore, the predictive power of tumor size was negatively impacted by the increase in T stage.
Furthermore, the discriminative ability of the Cox model based on the tumor-node-metastasis (TNM) system with tumor size outperformed the model based on the TNM system only.
Conclusion.
The current study identified tumor size as a critical clinical prognostic signature for esophageal cancer with considerable discriminatory ability and prognostic value.
Therefore, tumor size should be included in the American Joint Committee on Cancer (AJCC) TNM staging of T1-2 esophagus cancer patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Zilong& Yu, Bentong. 2020. Tumor Size as a Critical Prognostic Factor in T1-2 Stage Esophageal Cancer. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1166726
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Zilong& Yu, Bentong. Tumor Size as a Critical Prognostic Factor in T1-2 Stage Esophageal Cancer. Gastroenterology Research and Practice No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1166726
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Zilong& Yu, Bentong. Tumor Size as a Critical Prognostic Factor in T1-2 Stage Esophageal Cancer. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1166726
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166726
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر