Preeclampsia and the Risk of Pancreatitis: A Nationwide, Population-Based Cohort Study
المؤلفون المشاركون
Kao, Chia-Hung
Lin, Cheng-Li
Huang, Jia-Lun
Chen, Wei-Kung
Shih, Hong-Mo
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-30
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Preeclampsia is a multiple organ dysfunction during pregnancy, including hepatic, renal, and neurological dysfunction, and is defined as hypertension and proteinuria occurring after 20 weeks of pregnancy.
Clinical features seen in preeclampsia are due to relatively poorly perfused placenta and maternal endothelial dysfunction.
Some studies have found that preeclampsia may cause acute pancreatitis due to microvascular abnormalities and visceral ischemia.
This retrospective cohort study used the Taiwanese National Health Insurance Research Databases (NHIRD) to study the relationship between preeclampsia and the risk of pancreatitis.
Methods.
In total, 606,538 pregnant women were selected from the NHIRD between January 1, 1998 and December 31, 2010.
They were divided into a preeclampsia cohort (n=485,211) and a nonpreeclampsia cohort (n=121,327).
After adjusting for comorbidities that may induce pancreatitis, we analyzed and compared the incidence of pancreatitis in the two cohorts.
Results.
The overall incidence of pancreatitis in the preeclampsia cohort was significantly higher than that in the control cohort (4.29 vs.
2.33 per 10,000 person-years).
The adjusted HR of developing pancreatitis increased 1.68-fold (95% CI: 1.19-2.36) in the preeclampsia cohort.
In addition, pregnant women with preeclampsia without comorbidities had a significantly high risk of pancreatitis (aHR=1.83, 95% CI 1.27-2.63).
The combined effect of preeclampsia and alcohol-related diseases resulted in the highest risk of pancreatitis (aHR=43.4, 95% CI: 6.06-311.3).
Conclusion.
Compared with patients without preeclampsia, the risk of pancreatitis in patients with preeclampsia is significantly increased after adjusting for demographics and comorbidities.
The risk of pancreatitis is greatly increased when preeclampsia is accompanied by alcohol-related diseases, hepatitis C, gallstones, diabetes, or age of 26–35 years.
Early identification and effective control of preeclampsia and the associated comorbidities can reduce the risk of pancreatitis and the associated morbidity and mortality.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Huang, Jia-Lun& Chen, Wei-Kung& Lin, Cheng-Li& Kao, Chia-Hung& Shih, Hong-Mo. 2020. Preeclampsia and the Risk of Pancreatitis: A Nationwide, Population-Based Cohort Study. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1166758
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Huang, Jia-Lun…[et al.]. Preeclampsia and the Risk of Pancreatitis: A Nationwide, Population-Based Cohort Study. Gastroenterology Research and Practice No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1166758
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Huang, Jia-Lun& Chen, Wei-Kung& Lin, Cheng-Li& Kao, Chia-Hung& Shih, Hong-Mo. Preeclampsia and the Risk of Pancreatitis: A Nationwide, Population-Based Cohort Study. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1166758
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166758
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر