Synthesis of Interleukin-10 in Patients with Ulcerative Colitis and Helicobacter pylori Infection
المؤلفون المشاركون
Fonseca-Camarillo, G.
Barrera-Ochoa, Carlos A.
Yamamoto-Furusho, Jesús K.
Furuzawa-Carballeda, Janette
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background/Aims.
Epidemiological evidence suggests a relationship between Helicobacter pylori infection with the development of autoimmune diseases.
H.
pylori elicit a chronic systemic inflammatory response with the secretion of proinflammatory cytokines.
IL-10 is a regulatory cytokine that plays a central role in limiting host immune response to pathogen.
Increased IL-10 levels were reported in H.
pylori–infected gastric mucosa.
The aim of this study was to explore the relationship between IL-10 systemic synthesis and H.
pylori infection in patients with ulcerative colitis.
Methods.
Detection of H.
pylori infection was performed by a 13C-urea breath test in 31 patients with UC.
In each patient, a serum sample was drawn to measure IL-10 by the ELISA technique.
Based on the primary breath test result, two groups were formed and serum IL-10 was measured.
Results.
Serological IL-10 levels in patients with UC and negative 13C-urea breath test was 10.28 pg/ml whereas in patients with UC and positive 13C-urea breath test was 5.5 pg/ml (P=0.035).
IL-10 levels were higher in the inflammatory endoscopic and histological active groups which tested positive in the 13C-urea breath tests for H.
pylori (P<0.05).Conclusions.
The role of IL-10 secretion in patients with UC in determining the clinicopathological outcome of infection merits further study.
This study suggests an association between serum IL-10 and disease severity in patients with UC and HP infection.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yamamoto-Furusho, Jesús K.& Fonseca-Camarillo, G.& Barrera-Ochoa, Carlos A.& Furuzawa-Carballeda, Janette. 2020. Synthesis of Interleukin-10 in Patients with Ulcerative Colitis and Helicobacter pylori Infection. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1166827
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yamamoto-Furusho, Jesús K.…[et al.]. Synthesis of Interleukin-10 in Patients with Ulcerative Colitis and Helicobacter pylori Infection. Gastroenterology Research and Practice No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1166827
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yamamoto-Furusho, Jesús K.& Fonseca-Camarillo, G.& Barrera-Ochoa, Carlos A.& Furuzawa-Carballeda, Janette. Synthesis of Interleukin-10 in Patients with Ulcerative Colitis and Helicobacter pylori Infection. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1166827
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166827
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر