Predictive and Prognostic Factors of Synchronous Colorectal Lung-Limited Metastasis
المؤلفون المشاركون
Liu, Da
Li, Yuqiang
Zhou, Zhongyi
Tan, Fengbo
Liu, Wenxue
Zhou, Ming
Zhu, Hong
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-23
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Aim.
This study is aimed at investigating predictive and prognostic factors of synchronous colorectal lung-limited metastasis (SCLLM) based on The Surveillance, Epidemiology, and End Results (SEER) database.
Methods.
A multivariate logistic regression model was constructed to identify independent predictors of SCLLM.
A multivariate Cox proportional hazards regression model was used to distinguish independent prognostic factors.
Results.
This study enrolled 168,007 colorectal cancer (CRC) patients without metastatic diseases and 1,298 cases with SCLLM.
Eight features, involving race, tumor location, pathological grade, histological type, T stage, N stage, and tumor size as well as CEA, could be used as the independent predictors.
As the nomogram shown, the T4 stage contributed the most to SCLLM, followed by the N2 stage, elevated CEA, and rectal cancer.
A multivariate regression analysis discriminated 9 independent prognostic factors, including age, race, marital status, pathological grade, T stage, colectomy/proctectomy, chemotherapy, CEA, and TD.
The prognostic nomogram illustrated that nonresection/NOS played as the poorest prognostic factor, followed by nonchemotherapy, ≥75-year old and T4 stage.
The cumulative survival curves revealed the influence of each prognostic factor on survival after controlling the other variables.
Conclusions.
This study identified independent predictors and prognostic factors for SCLLM based on a large database of the United States.
The predictors and prognostic factors can provide supporting evidence for the prevention and treatment of SCLLM.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Yuqiang& Zhou, Zhongyi& Liu, Da& Zhou, Ming& Tan, Fengbo& Liu, Wenxue…[et al.]. 2020. Predictive and Prognostic Factors of Synchronous Colorectal Lung-Limited Metastasis. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1166914
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Yuqiang…[et al.]. Predictive and Prognostic Factors of Synchronous Colorectal Lung-Limited Metastasis. Gastroenterology Research and Practice No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1166914
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Yuqiang& Zhou, Zhongyi& Liu, Da& Zhou, Ming& Tan, Fengbo& Liu, Wenxue…[et al.]. Predictive and Prognostic Factors of Synchronous Colorectal Lung-Limited Metastasis. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1166914
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166914
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر