Clinicopathological Features and Prognostic Implication of Gastric Carcinoma with Lymphoid Stroma
المؤلفون المشاركون
Pyo, Jung-Soo
Kim, Nae Yu
Son, Byoung Kwan
Lee, Hyo Young
Oh, Il Hwan
Chung, Kwang Hyun
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-03
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background/Objective.
Gastric carcinoma with lymphoid stroma (GCLS) has been referred to as lymphoepithelioma-like carcinoma and medullary carcinoma.
The present study aims at elucidating the clinicopathologic features and prognostic implications of GCLS through a meta-analysis.
Methods.
This study included 34 eligible studies and 1757 GCLSs.
The clinicopathologic characteristics of GCLS were investigated from eligible studies, and the meta-analysis was performed.
In addition, we compared the survival rates between GCLS and non-GCLS.
Results.
The estimated rate of GCLS was 0.062 (95% confidence interval (CI) 0.040-0.097).
GCLS was significantly correlated with the diffuse type of Lauren’s classification, proximal tumor location, less-frequent lymphatic invasion, and lower pTNM stage.
However, there was no significant difference in age, sex, tumor differentiation, vascular invasion, perineural invasion, pT stage, lymph node metastasis, and distant metastasis between GCLS and non-GCLS patients.
EBV positive rates in GCLS and non-GCLS patients were 0.723 (95% CI 0.643-0.791) and 0.064 (95% CI 0.039-0.103), respectively.
HER2 expression in GCLS was significantly lower than that in non-GCLS.
GCLS patients had a more favorable prognosis than that of non-GCLS patients (hazard ratio 0.500, 95% CI 0.305-0.821).
Conclusion.
GCLS comprised 6.2% of overall GC and more frequent in the proximal portion of the stomach.
Since GCLS was associated with better prognosis, the histologic finding can be useful for predicting the patient’s prognosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pyo, Jung-Soo& Kim, Nae Yu& Son, Byoung Kwan& Lee, Hyo Young& Oh, Il Hwan& Chung, Kwang Hyun. 2020. Clinicopathological Features and Prognostic Implication of Gastric Carcinoma with Lymphoid Stroma. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1166952
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pyo, Jung-Soo…[et al.]. Clinicopathological Features and Prognostic Implication of Gastric Carcinoma with Lymphoid Stroma. Gastroenterology Research and Practice No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1166952
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pyo, Jung-Soo& Kim, Nae Yu& Son, Byoung Kwan& Lee, Hyo Young& Oh, Il Hwan& Chung, Kwang Hyun. Clinicopathological Features and Prognostic Implication of Gastric Carcinoma with Lymphoid Stroma. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1166952
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1166952
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر