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Log Odds of Positive Lymph Node- (LODDS-) Based Competing-Risk Nomogram for Predicting Prognosis of Resected Rectal Cancer: A Development and Validation Study
المؤلفون المشاركون
Zheng, Rui-zhe
Xie, Jiang
Zhang, Shui-qiang
Li, Wen
Dong, Bo
Cong, Yin-wei
Wang, Zhi-qiang
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-19
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background and Aims.
Cancer-specific survival (CSS) of rectal cancer (RC) is associated with several factors.
We aimed to build an efficient competing-risk nomogram based on log odds of positive lymph nodes (LODDS) to predict RC survival.
Methods.
Medical records of 8754 patients were collected from the Surveillance, Epidemiology, and End Results (SEER) database, of 4895 patients from SEER during 2011–2014 and of 478 patients from an Eastern center as a development cohort, validation cohort, and test cohort, respectively.
Univariate and multivariate competing-risk analyses were performed to build competing-risk nomogram for predicting the CSS of RC patients.
Prediction efficacy was evaluated and compared with reference to the 8th TNM classification using the factor areas under the receiver operating characteristic curve (AUC) and Brier score.
Results.
The competing-risk nomogram was based on 6 variables: size, M stage, LODDS, T stage, grade, and age.
The competing-risk nomogram showed a higher AUC value in predicting the 5-year death rate due to RC than the 8th TNM stage in the development cohort (0.81 vs.
0.76), validation cohort (0.85 vs.
0.82), and test cohort (0.71 vs.
0.66).
The competing-risk nomogram also showed a higher Brier score in predicting the 5-year death rate due to RC than the 8th TNM stage in the development cohort (0.120 vs.
0.127), validation cohort (0.123 vs.
0.128), and test cohort (0.202 vs.
0.226).
Conclusion.
We developed and validated a competing-risk nomogram for RC death, which could provide the probability of survival averting competing risk to facilitate clinical decision-making.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zheng, Rui-zhe& Xie, Jiang& Zhang, Shui-qiang& Li, Wen& Dong, Bo& Cong, Yin-wei…[et al.]. 2020. Log Odds of Positive Lymph Node- (LODDS-) Based Competing-Risk Nomogram for Predicting Prognosis of Resected Rectal Cancer: A Development and Validation Study. Gastroenterology Research and Practice،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1167181
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zheng, Rui-zhe…[et al.]. Log Odds of Positive Lymph Node- (LODDS-) Based Competing-Risk Nomogram for Predicting Prognosis of Resected Rectal Cancer: A Development and Validation Study. Gastroenterology Research and Practice No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1167181
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zheng, Rui-zhe& Xie, Jiang& Zhang, Shui-qiang& Li, Wen& Dong, Bo& Cong, Yin-wei…[et al.]. Log Odds of Positive Lymph Node- (LODDS-) Based Competing-Risk Nomogram for Predicting Prognosis of Resected Rectal Cancer: A Development and Validation Study. Gastroenterology Research and Practice. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1167181
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1167181
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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