Cytokines as Biomarkers and Their Respective Clinical Cutoff Levels

المؤلفون المشاركون

Monastero, Rebecca N.
Pentyala, Srinivas

المصدر

International Journal of Inflammation

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-11، 11ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-04-09

دولة النشر

مصر

عدد الصفحات

11

التخصصات الرئيسية

الأمراض
الطب البشري

الملخص EN

Cytokines, including interleukins, interferons, tumor necrosis factors, and chemokines, have a variety of pro- and anti-inflammatory effects in the body through a number of biochemical pathways and interactions.

Stimuli, actions, interactions, and downstream effects of cytokines have been investigated in more depth in recent years, and clinical research has also been conducted to implicate cytokines in causal patterns in certain diseases.

However, particular cutoffs of cytokines as biomarkers for disease processes have not been well studied, and this warrants future work to potentially improve diagnoses for diseases with inflammatory markers.

A limited number of studies in this area are reviewed, considering diseases correlated with abnormal cytokine profiles, as well as specific cutoffs at which cytokines have been deemed clinically useful for diagnosing those diseases through Receiver Operator Characteristics modeling.

In light of studies such as those discussed in this review, cytokine testing has the potential to support diagnosis due to its lack of invasiveness and low cost, compared to other common types of testing for infections and inflammatory diseases.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Monastero, Rebecca N.& Pentyala, Srinivas. 2017. Cytokines as Biomarkers and Their Respective Clinical Cutoff Levels. International Journal of Inflammation،Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1167447

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Monastero, Rebecca N.& Pentyala, Srinivas. Cytokines as Biomarkers and Their Respective Clinical Cutoff Levels. International Journal of Inflammation No. 2017 (2017), pp.1-11.
https://search.emarefa.net/detail/BIM-1167447

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Monastero, Rebecca N.& Pentyala, Srinivas. Cytokines as Biomarkers and Their Respective Clinical Cutoff Levels. International Journal of Inflammation. 2017. Vol. 2017, no. 2017, pp.1-11.
https://search.emarefa.net/detail/BIM-1167447

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1167447