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The Lipodystrophy Syndrome in HIV-Infected Children under Antiretroviral Therapy: A First Report from the Central Africa
المؤلفون المشاركون
Aloni, Michel Ntetani
Ekila, Mathilde B.
Tshamala, Honoré Kalombayi
Aketi, Loukia
Tshibassu, Pierre Manianga
Mafuta, Eric Musalu
Kayembe, Patrick Kalambayi
Shiku, Joseph Diayisu
المصدر
International Journal of Pediatrics
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-03-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Despite the high prevalence of the HIV/AIDS, few studies focused on the prevalence of lipodystrophy in pediatric HIV patients on antiretroviral therapy (ARV) in sub-Saharan African countries.
The aim of this study was to assess the prevalence and to identify the risk factors of metabolic disorders related to ARV therapy in this population.
Methods.
A cross-sectional study was completed in Kinshasa, the Democratic Republic of Congo.
HIV-infected children aged between six and 18 years on ARV were consecutively recruited.
For each case, two control children (one non-HIV infected child and one HIV-infected antiretroviral therapy-naïve child) were also recruited.
Results.
80 HIV-infected on ARV therapy children (group 1), 80 noninfected children (group 2) and 65 HIV-infected antiretroviral therapy-naïve children (group 3) were recruited.
The frequency of lipoatrophy was not statistically different between group 1 (16.3%) and group 3 (21.5%).
A significantly higher proportion of lipohypertrophy, hypercholesterolemia, and lactic acidosis was noted in children of group 1, compared to the controls (p<0.05).
Mixed form was rarely observed in this series.
The frequency of hypertriglyceridemia was not different between the 3 groups (p>0.05).
Conclusion.
Lipohypertrophy, hypercholesterolemia, and lactic acidosis emerge as a frequent metabolic disorders due to ARV therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tshamala, Honoré Kalombayi& Aketi, Loukia& Tshibassu, Pierre Manianga& Ekila, Mathilde B.& Mafuta, Eric Musalu& Kayembe, Patrick Kalambayi…[et al.]. 2019. The Lipodystrophy Syndrome in HIV-Infected Children under Antiretroviral Therapy: A First Report from the Central Africa. International Journal of Pediatrics،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1167591
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tshamala, Honoré Kalombayi…[et al.]. The Lipodystrophy Syndrome in HIV-Infected Children under Antiretroviral Therapy: A First Report from the Central Africa. International Journal of Pediatrics No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1167591
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tshamala, Honoré Kalombayi& Aketi, Loukia& Tshibassu, Pierre Manianga& Ekila, Mathilde B.& Mafuta, Eric Musalu& Kayembe, Patrick Kalambayi…[et al.]. The Lipodystrophy Syndrome in HIV-Infected Children under Antiretroviral Therapy: A First Report from the Central Africa. International Journal of Pediatrics. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1167591
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1167591
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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