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Renal Function and Death in Older Women: Which eGFR Formula Should We Use?
المؤلفون المشاركون
Taylor, Brent C.
Canales, Muna T.
Blackwell, Terri
Ishani, Areef
Hart, Allyson
Beyth, Rebecca J.
Ensrud, Kristine E.
المصدر
International Journal of Nephrology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-29
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
The Berlin Initiative Study (BIS) eGFR equations were developed specifically for aged populations, but their predictive validity compared to standard formulae is unknown in older women.
Methods.
In a prospective study of 1289 community-dwelling older women (mean age 79.5 years), we compared the performance of the BIS1 SCr-based equation to the CKD-EPIcr and the BIS2 SCr- and Scysc-based equation to the CKD-EPIcr,cysc to predict cardiovascular and all-cause mortality.
Results.
Prevalence of specific eGFR category (i.e., ≥75, 60–74, 45–59, and <45) according to eGFR equation was 12.3%, 38.4%, 37.3%, and 12.0% for BIS1; 48.3%, 27.8%, 16.2%, and 7.8% for CKD-EPIcr; 14.1%, 38.6%, 37.6%, and 9.6% for BIS2; and 33.5%, 33.4%, 22.0%, and 11.1% for CKD-EPIcr,cysc, respectively.
Over 9±4 years, 667 (51.8%) women died.
For each equation, women with eGFR <45 were at increased risk of mortality compared to eGFR ≥75 [adjusted HR (95% CI): BIS1, 1.5 (1.1–2.0); CKD-EPIcr, 1.7 (1.3–2.2); BIS2, 2.0 (1.4–2.8); CKD-EPIcr,cysc, 1.8 (1.4–2.3); p-trend <0.01].
Net reclassification analyses found no material difference in discriminant ability between the BIS and CKD-EPI equations.
Results were similar for cardiovascular death.
Conclusions.
Compared to CKD-EPI, BIS equations identified a greater proportion of older women as having CKD but performed similarly to predict mortality risk.
Thus, the BIS equations should not replace CKD-EPI equations to predict risk of death in older women.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Canales, Muna T.& Blackwell, Terri& Ishani, Areef& Taylor, Brent C.& Hart, Allyson& Beyth, Rebecca J.…[et al.]. 2017. Renal Function and Death in Older Women: Which eGFR Formula Should We Use?. International Journal of Nephrology،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1167848
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Canales, Muna T.…[et al.]. Renal Function and Death in Older Women: Which eGFR Formula Should We Use?. International Journal of Nephrology No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1167848
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Canales, Muna T.& Blackwell, Terri& Ishani, Areef& Taylor, Brent C.& Hart, Allyson& Beyth, Rebecca J.…[et al.]. Renal Function and Death in Older Women: Which eGFR Formula Should We Use?. International Journal of Nephrology. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1167848
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1167848
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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