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Assessing the Impact of Isoniazid Preventive Therapy (IPT) on Tuberculosis Incidence and Predictors of Tuberculosis among Adult Patients Enrolled on ART in Nekemte Town, Western Ethiopia: A Retrospective Cohort Study
المؤلفون المشاركون
Tiruneh, Gemechu
Getahun, Alemayehu
Adeba, Emiru
المصدر
Interdisciplinary Perspectives on Infectious Diseases
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Isoniazid preventive therapy is a prophylactic treatment used in the prevention of active tuberculosis.
It is known to be most effective in preventing tuberculosis in patients with positive tuberculin skin test.
Methods.
A retrospective cohort study centering on two institutions in Nekemte town, Western Ethiopia, was employed.
Secondary data of 600 medical records were analyzed by Cox regression.
Result.
Tuberculosis incidence among the Isoniazid treated group was 1.98 per 100 person-years and 4.52 per 100 person-years in the untreated group.
CD4 cell count, clinical staging, body mass index (BMI), not using cotrimoxazole, body weight, and functional status were significant predictors of tuberculosis risk.
Isoniazid preventive therapy use was associated with 55% reduction of tuberculosis incidence.
Conclusion.
Isoniazid preventive therapy use was associated with significant reduction in tuberculosis incidence, even in the absence of Tuberculin Skin Test (TST).
Therefore, isoniazid preventive therapy (IPT) coverage should be used more widely, with special emphasis given to patients at higher risk of tuberculosis.
The study shows that the absence of TST testing should not be a limitation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tiruneh, Gemechu& Getahun, Alemayehu& Adeba, Emiru. 2019. Assessing the Impact of Isoniazid Preventive Therapy (IPT) on Tuberculosis Incidence and Predictors of Tuberculosis among Adult Patients Enrolled on ART in Nekemte Town, Western Ethiopia: A Retrospective Cohort Study. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1168755
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tiruneh, Gemechu…[et al.]. Assessing the Impact of Isoniazid Preventive Therapy (IPT) on Tuberculosis Incidence and Predictors of Tuberculosis among Adult Patients Enrolled on ART in Nekemte Town, Western Ethiopia: A Retrospective Cohort Study. Interdisciplinary Perspectives on Infectious Diseases No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1168755
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tiruneh, Gemechu& Getahun, Alemayehu& Adeba, Emiru. Assessing the Impact of Isoniazid Preventive Therapy (IPT) on Tuberculosis Incidence and Predictors of Tuberculosis among Adult Patients Enrolled on ART in Nekemte Town, Western Ethiopia: A Retrospective Cohort Study. Interdisciplinary Perspectives on Infectious Diseases. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1168755
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1168755
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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