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Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin
المؤلفون المشاركون
Kolosov, Victor
Perelman, Juliy
Kozlov, Roman S.
Chuchalin, Alexander
Onishchenko, Gennadiy G.
Kurganova, Olga P.
Zaitseva, Tatiana A.
Manakov, Leonid G.
Kholodok, Galina N.
Ivakhnishina, Natalia M.
Trotsenko, Olga E.
Bondarenko, Albina P.
المصدر
Interdisciplinary Perspectives on Infectious Diseases
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-02-18
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Pneumococcal infection being one of the dominant causes of acute respiratory diseases and exacerbation of chronic ones is a serious problem for human health and society.
The flood in the Amur river basin in the summer of 2013 created a special zone and risk conditions for the formation of respiratory pathology in the Far-Eastern region of Russia.
We aimed to give clinical and epidemiological assessment of the effectiveness of vaccination programs of respiratory viral and pneumococcal infections and generalization of regional experience in the organization of a set of measures aimed at their prevention in the postflood period in the Far-Eastern region.
Methods.
The monitoring program includes children aged 2 to 5 years in the amount of 4988 with risk factors for pneumococcal infection.
The pneumococcal conjugate vaccine Prevenar-13 was used for immunization.
Data on the incidence of ARVI and pneumonia in children in pre- and postvaccination periods were to be recorded.
The indicators and special criteria were used to assess the effectiveness of vaccination.
To study the circulation of serovariants of pneumococcus in inflammatory diseases of the respiratory tract and nasopharyngeal carrier, bacteriological and molecular genetic methods (RT-PCR in the mode of multiprime detection) were used.
Results.
Differences in the frequency and range of serovariants of circulating isolates of pneumococcus in the postvaccinal period and in unvaccinated children, elimination of a number of serotypes, and appearance of circulation of nonvaccinated strains were revealed.
The incidence of acute respiratory diseases and pneumonia among the vaccinated population for 2 years in the region decreased by 2.5 times.
The coefficient of effectiveness of vaccination according to the indicator of morbidity of children with pneumonia reaches 75-100% with direct dependence on the age of children (r=0.98).
Conclusion.
Comparative statistical analysis revealed a high degree of effectiveness of regional programs with the methods of immunoprophylaxis of pneumococcal infections.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chuchalin, Alexander& Onishchenko, Gennadiy G.& Kolosov, Victor& Kurganova, Olga P.& Zaitseva, Tatiana A.& Manakov, Leonid G.…[et al.]. 2019. Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin. Interdisciplinary Perspectives on Infectious Diseases،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1168772
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chuchalin, Alexander…[et al.]. Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin. Interdisciplinary Perspectives on Infectious Diseases No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1168772
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chuchalin, Alexander& Onishchenko, Gennadiy G.& Kolosov, Victor& Kurganova, Olga P.& Zaitseva, Tatiana A.& Manakov, Leonid G.…[et al.]. Vaccine Prophylaxis of Pneumococcal Infections in Children under Conditions of Severe Flood in the Amur River Basin. Interdisciplinary Perspectives on Infectious Diseases. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1168772
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1168772
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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