Quantitative Characteristics of Toxic Compounds According to the Solvent Type
المؤلفون المشاركون
Kim, Yong-Hyun
An, Young-Ji
Choi, Seong-Jin
Lee, Kyuhong
المصدر
Journal of Analytical Methods in Chemistry
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-04-30
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
The quantitative analysis of target substances is an important part of assessing the toxicity of diverse materials.
Usually, the quantitation of target compounds is conducted by instrumental analysis such as chromatography and capillary electrophoresis.
If solvents are used in the pretreatment step of the target analyte quantification, it would be crucial to examine the solvent effect on the quantitative analysis.
Therefore, in this study, we assessed the solvent effects using four different solvents (methanol, hexane, phosphate buffered saline (PBS), and dimethyl sulfoxide (DMSO)) and three toxic compounds (benzene, toluene, and methylisothiazolinone (MIT)).
Liquid working standards containing the toxic compounds were prepared by dilution with each solvent and analyzed by gas chromatography-mass spectrometry (GC-MS).
As a result, we found that the response factor (RF) values of the target analytes were different, depending on the solvent types.
In particular, benzene and toluene exhibited their highest RF values (33,674 ng−1 and 78,604 ng−1, respectively) in hexane, while the RF value of MIT was the highest (9,067 ng−1) in PBS.
Considering the correlation (R2) and relative standard deviation (RSD) values, all target analytes showed fairly good values (R2 > 0.99 and RSD < 10%) in methanol and DMSO.
In contrast, low R2 (0.0562) and high RSD (10.6%) values of MIT were detected in hexane, while benzene and toluene exhibited relatively low R2 and high RSD values in PBS (mean R2 = 0.9892 ± 0.0146 and mean RSD = 13.3 ± 4.1%).
Based on these findings, we concluded that the results and reliability of the quantitative analysis change depending on the analyte and solvent types.
Therefore, in order to accurately assess the toxicity of target compounds, reliable analytical data should be obtained, preferentially by considering the solvent types.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
An, Young-Ji& Choi, Seong-Jin& Kim, Yong-Hyun& Lee, Kyuhong. 2019. Quantitative Characteristics of Toxic Compounds According to the Solvent Type. Journal of Analytical Methods in Chemistry،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1169110
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
An, Young-Ji…[et al.]. Quantitative Characteristics of Toxic Compounds According to the Solvent Type. Journal of Analytical Methods in Chemistry No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1169110
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
An, Young-Ji& Choi, Seong-Jin& Kim, Yong-Hyun& Lee, Kyuhong. Quantitative Characteristics of Toxic Compounds According to the Solvent Type. Journal of Analytical Methods in Chemistry. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1169110
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1169110
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر