Identification and Characterization of Key Chemical Constituents in Processed Gastrodia elata Using UHPLC-MSMS and Chemometric Methods

المؤلفون المشاركون

Avula, Bharathi
Ye, Xide
Wang, Yanhong
Zhao, Jianping
Wang, Mei
Peng, Qiaozhen
Ouyang, Hui
Lingyun, Zhong
Zhang, Jinlian
Khan, Ikhlas A.

المصدر

Journal of Analytical Methods in Chemistry

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-10-23

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

الكيمياء

الملخص EN

Gastrodia elata Blume belongs to the Orchidaceae family.

G.

elata is often processed when used in traditional Chinese medicine (TCM).

In the current study, a traditional processing method, known as “Jianchang Bang,” was applied.

Steamed and dried (S&D) G.

elata was processed with ginger juice for up to 5 days (GEP5D).

An UHPLC-MS/MS combined with a chemometric method was developed for the analysis of processed G.

elata along with the raw material as well as steamed and dried G.

elata.

As a result, the primary marker compounds were identified with the aid of TOF-MS and MS/MS analyses.

Compared with the raw material of G.

elata with GEP5D, three new parishin-type compounds were identified according to their retention time, accurate mass, and fragmentation patterns.

The chromatographic peak areas for marker compounds, including S-(gastrodin)-glutathione, S-(4-hydroxybenzylamine)-glutathione, and parishin-type compounds, changed significantly.

This result indicated that by applying the “Jianchang Bang” method, changes in chemical composition in G.

elata contents were observed.

The study also demonstrated that chemometric analysis is helpful in understanding the processing mechanism and will provide scientific support for the clinical application of G.

elata.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Ye, Xide& Wang, Yanhong& Zhao, Jianping& Wang, Mei& Avula, Bharathi& Peng, Qiaozhen…[et al.]. 2019. Identification and Characterization of Key Chemical Constituents in Processed Gastrodia elata Using UHPLC-MSMS and Chemometric Methods. Journal of Analytical Methods in Chemistry،Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1169150

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Ye, Xide…[et al.]. Identification and Characterization of Key Chemical Constituents in Processed Gastrodia elata Using UHPLC-MSMS and Chemometric Methods. Journal of Analytical Methods in Chemistry No. 2019 (2019), pp.1-10.
https://search.emarefa.net/detail/BIM-1169150

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Ye, Xide& Wang, Yanhong& Zhao, Jianping& Wang, Mei& Avula, Bharathi& Peng, Qiaozhen…[et al.]. Identification and Characterization of Key Chemical Constituents in Processed Gastrodia elata Using UHPLC-MSMS and Chemometric Methods. Journal of Analytical Methods in Chemistry. 2019. Vol. 2019, no. 2019, pp.1-10.
https://search.emarefa.net/detail/BIM-1169150

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1169150